Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1957791..1957931 Replicon chromosome
Accession NZ_CP058353
Organism Serratia marcescens strain ESE2014

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1957835..1957931 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1957791..1957931 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HW877_RS09335 (HW877_09345) 1953059..1953454 + 396 WP_033640666.1 RidA family protein -
HW877_RS09340 (HW877_09350) 1953611..1954564 + 954 WP_033641435.1 prolyl aminopeptidase -
HW877_RS09345 (HW877_09355) 1954596..1954826 - 231 WP_016928156.1 DNA polymerase III subunit theta -
HW877_RS09350 (HW877_09360) 1955171..1955689 + 519 WP_015377481.1 non-heme ferritin -
HW877_RS09355 (HW877_09365) 1955982..1956398 + 417 WP_042706245.1 CopC domain-containing protein YobA -
HW877_RS09360 (HW877_09370) 1956401..1957282 + 882 WP_244758097.1 copper homeostasis membrane protein CopD -
HW877_RS09365 (HW877_09375) 1957352..1957693 + 342 WP_244758098.1 YebY family protein -
- 1957791..1957931 - 141 - - Antitoxin
- 1957835..1957931 + 97 - - Toxin
HW877_RS09370 (HW877_09380) 1958010..1959092 - 1083 WP_244758099.1 phage integrase Arm DNA-binding domain-containing protein -
HW877_RS09375 (HW877_09385) 1959067..1959342 - 276 WP_015377485.1 excisionase -
HW877_RS09380 (HW877_09390) 1959418..1960485 - 1068 WP_244758100.1 RecT family recombinase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 1949773..2018537 68764


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 97 bp

>T166656 NZ_CP058353:1957835-1957931 [Serratia marcescens]
AACAAGCCCTGCATTAAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTAGACCGAATATAGGAATC
GTATTCGGTCTTTTTTT

Antitoxin


Download         Length: 141 bp

>AT166656 NZ_CP058353:c1957931-1957791 [Serratia marcescens]
AAAAAAAGACCGAATACGATTCCTATATTCGGTCTAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCAT
TTAATGCAGGGCTTGTTCAGCCGTGCACTTTAAGAGTAGCCTACCGCGCCAGTTTTGCCAG

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References