Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 3227404..3228206 Replicon chromosome
Accession NZ_CP058350
Organism Rhizobium sp. ADMK78

Toxin (Protein)


Gene name TacT3 Uniprot ID -
Locus tag FE840_RS15720 Protein ID WP_138286427.1
Coordinates 3227404..3227931 (-) Length 176 a.a.

Antitoxin (Protein)


Gene name TacA3 Uniprot ID -
Locus tag FE840_RS15725 Protein ID WP_138286429.1
Coordinates 3227928..3228206 (-) Length 93 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FE840_RS15705 3223349..3224272 + 924 WP_138286422.1 alpha/beta hydrolase -
FE840_RS15710 3224448..3225671 + 1224 WP_138286424.1 CoA transferase -
FE840_RS15715 3225668..3227323 + 1656 WP_138286425.1 thiamine pyrophosphate-binding protein -
FE840_RS15720 3227404..3227931 - 528 WP_138286427.1 GNAT family N-acetyltransferase Toxin
FE840_RS15725 3227928..3228206 - 279 WP_138286429.1 DUF1778 domain-containing protein Antitoxin
FE840_RS15730 3228448..3228789 - 342 WP_138286430.1 RidA family protein -
FE840_RS15735 3228875..3229213 - 339 WP_138286431.1 TIGR01244 family phosphatase -
FE840_RS15740 3229299..3230129 - 831 WP_138286432.1 DUF4432 family protein -
FE840_RS15745 3230425..3231765 + 1341 WP_138286433.1 L,D-transpeptidase -
FE840_RS15750 3231830..3232549 - 720 WP_171033671.1 ParA family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Vibrio phage ICP1, Orf50

(11-87)


Sequences

Toxin        


Download         Length: 176 a.a.        Molecular weight: 18894.85 Da        Isoelectric Point: 8.1815

>T166650 WP_138286427.1 NZ_CP058350:c3227931-3227404 [Rhizobium sp. ADMK78]
MRIPHWHEEPIGKSHDRASFDCGNAQMNEFLLRFARQSHEHNAAKTFCAIDTARPGRILGFYTIAPCSVAHETVPAAMTK
GMARHEVPGFRLARLATDIGVAGQGLGGELLAAAALRCLRLAGEGGGILLLIDAKDERAAHWYASFGAEPLREKPLTLVM
PLATFAADLRAKGLL

Download         Length: 528 bp

>T166650 NZ_CP074366:273622-273852 [Escherichia coli]
CTGGATCAGCTATTTAAATCACCTTTACCTCAAGGAATCAAATGGACTGATATAGAATCTCTGGTTAAAGCGTTAGGCGG
AGAAATTAAGGAAGGTAGGGGGTCGCGCTGTAAGTTCATACTAAATATGAGCGTTGCGTGTTTCCATCGGCCTCATCCGT
CGCCAGATACCGATAAAGGCGCTGTAGAAAGCGTGCGTGACTGGTTACTAAGTATAGGGGTAAAACCATGA

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 10101.73 Da        Isoelectric Point: 8.8547

>AT166650 WP_138286429.1 NZ_CP058350:c3228206-3227928 [Rhizobium sp. ADMK78]
MPRAVVEDNERMSLRIAASAKSKLLRAAMLRNTDLTNFVTQSALREAEAVIAEAEAIQVSERDHLRILTLLENPPKPNAK
LRAAIAALPDTL

Download         Length: 279 bp

>AT166650 NZ_CP074366:273849-274208 [Escherichia coli]
ATGATCAAACTGAAGACGCCAAACTCTATGGAGATTGCCGGGCAACCTGCTGTTATCACTTACGTGCCAGAACTGAATGC
ATTTCGTGGCAAATTCCTGGGCTTGTCAGGTTATTGTGATTTTGTCTCTGACAGCATTCAGGGGCTGCAAAAAGAAGGGG
AACTTTCCCTGCGAGAGTATCTTGAGGATTGTAAAGCTGCGGGTATTGAGCCGTATGCGCGTACAGAAAAGATTAAGACC
TTTACGTTACGCTATCCAGAATCGCTGAGTGAACGCCTTAATAATGCGGCTGCGCAGCAACAAGTCTCTGTTAATACCTA
TATTATTGAAACACTGAATGAGCGTTTGAATCATTTATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References