Detailed information of TA system TA166649

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): yoeB-relE/YoeB-YefM
• Location: 2543252..2543757
• Replicon: chromosome
• Accession: NZ_CP058350
• Organism: Rhizobium sp. ADMK78

Toxin (Protein)

• Gene name: yoeB
• Uniprot ID: -
• Locus tag: FE840_RS12400
• Protein ID: WP_138288966.1
• Coordinates: 2543252..2543506 (-)
• Length: 85 a.a.

Antitoxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: FE840_RS12405
• Protein ID: WP_138288965.1
• Coordinates: 2543503..2543757 (-)
• Length: 85 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
FE840_RS12375	2539003..2540433	-	1431	WP_138288970.1	3-mercaptopyruvate sulfurtransferase	-
FE840_RS12380	2540455..2541192	-	738	WP_138288969.1	alanyl-tRNA editing protein	-
FE840_RS12385	2541218..2542258	-	1041	WP_138288968.1	cysteine synthase A	-
FE840_RS12390	2542468..2542914	-	447	WP_138288967.1	type II toxin-antitoxin system VapC family toxin	-
FE840_RS12395	2542907..2543161	-	255	WP_210271767.1	type II toxin-antitoxin system prevent-host-death family antitoxin	-
FE840_RS12400	2543252..2543506	-	255	WP_138288966.1	Txe/YoeB family addiction module toxin	Toxin
FE840_RS12405	2543503..2543757	-	255	WP_138288965.1	type II toxin-antitoxin system prevent-host-death family antitoxin	Antitoxin
FE840_RS12410	2544023..2544712	+	690	WP_138288964.1	hypothetical protein	-
FE840_RS12415	2544773..2546236	-	1464	WP_138288963.1	DNA photolyase family protein	-
FE840_RS12420	2546372..2546599	-	228	WP_138288962.1	hypothetical protein	-
FE840_RS12430	2546993..2547268	+	276	WP_171033791.1	hypothetical protein	-
FE840_RS12440	2547669..2548340	+	672	WP_171033790.1	protein-L-isoaspartate O-methyltransferase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin YoeB (2-84)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-72)

Sequences

Toxin

Protein

• Length: 85 a.a.
• Molecular weight: 10117.56 Da
• Isoelectric Point: 9.9073

>T166649 WP_138288966.1 NZ_CP058350:c2543506-2543252 [Rhizobium sp. ADMK78]
VKLIFHARAWEDYLYWQSSDPKMLARINQLIKESSRSPFQGIGKPEPLRGELRGWWSRRIDQEHRLVYRPTDDGLLIAQC
RHHY

Nucleotide

• Length: 255 bp

>T166649 NZ_CP074365:c4367668-4367516 [Xanthomonas translucens]
ATGAAGCGACTGTTCACCTTGACGATGCTGACCCTGTTTTGTGCAGGCATGCTGACCGGCTGCAACACCATGGCCGGCGC
CGGTAAGGACATGCAGAAGGCCGGCGATAAGGTGGAAACCAAGGCCGACGACTGTAAAGACGGCAAGTGCTGA

Antitoxin

Protein

• Length: 85 a.a.
• Molecular weight: 9492.62 Da
• Isoelectric Point: 4.6812

>AT166649 WP_138288965.1 NZ_CP058350:c2543757-2543503 [Rhizobium sp. ADMK78]
MRTTSYSDLRKNLASLLDSVTDDRTPVLITRDRGKPAAVLMSVEDFASYEETQHLLKSPRNAERLLEAVRDLDEGKGDVR
ELSE

Nucleotide

• Length: 255 bp

>AT166649 NZ_CP074365:c4367417-4367283 [Xanthomonas translucens]
ATGAAGCGTACTTTCGCGTGGATGCTGCTGGCGATGTTCTCGGTGGGCCTGCTGTCGGGCTGCAACACGGTTGCCGGTGC
CGGCAAGGACGTGAAGAGCGCCGGCGAGAAGGTCGAAGACGCCGCCAAGAACTGA