166648

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/PemK-MazE
Location 2071585..2072132 Replicon chromosome
Accession NZ_CP058350
Organism Rhizobium sp. ADMK78

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag FE840_RS10015 Protein ID WP_138288230.1
Coordinates 2071585..2071893 (-) Length 103 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag FE840_RS10020 Protein ID WP_138288229.1
Coordinates 2071905..2072132 (-) Length 76 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FE840_RS09990 2066897..2067703 + 807 WP_138288400.1 hypothetical protein -
FE840_RS09995 2067700..2068014 - 315 WP_138288232.1 type II toxin-antitoxin system RelE/ParE family toxin -
FE840_RS10000 2068011..2068238 - 228 WP_138288399.1 ribbon-helix-helix protein, CopG family -
FE840_RS10005 2068362..2070563 - 2202 WP_138288231.1 PBP1A family penicillin-binding protein -
FE840_RS10010 2070755..2071219 + 465 WP_138288398.1 YcgN family cysteine cluster protein -
FE840_RS10015 2071585..2071893 - 309 WP_138288230.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
FE840_RS10020 2071905..2072132 - 228 WP_138288229.1 antitoxin MazE family protein Antitoxin
FE840_RS10025 2072208..2073002 - 795 WP_138288228.1 hypothetical protein -
FE840_RS10030 2073190..2073642 + 453 WP_138288227.1 MarR family transcriptional regulator -
FE840_RS10035 2073639..2074271 + 633 WP_138288226.1 isochorismatase family protein -
FE840_RS10040 2074518..2074955 + 438 WP_138288225.1 hypothetical protein -
FE840_RS10045 2074981..2075502 - 522 WP_138288224.1 N-acetyltransferase -
FE840_RS10050 2075637..2075939 + 303 WP_138288223.1 type II toxin-antitoxin system RelB/DinJ family antitoxin -
FE840_RS10055 2075936..2076220 + 285 Protein_1973 type II toxin-antitoxin system RelE/ParE family toxin -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(10-100)

Antitoxin

Antitoxin MazE-like

(7-69)


Sequences

Toxin        


Download         Length: 103 a.a.        Molecular weight: 10913.89 Da        Isoelectric Point: 8.8975

>T166648 WP_138288230.1 NZ_CP058350:c2071893-2071585 [Rhizobium sp. ADMK78]
IVTVAISGDFGKPRPALIIQSDSFQDTGTVTVLLMTSTVIEASLLRISVSPTPLNGLTLPSQIMVDKIMSIRRDKVGRLI
GQLDEATMLQVTRSLAVFMGIG

Download         Length: 309 bp

>T166648 NZ_CP074365:c4367417-4367283 [Xanthomonas translucens]
ATGAAGCGTACTTTCGCGTGGATGCTGCTGGCGATGTTCTCGGTGGGCCTGCTGTCGGGCTGCAACACGGTTGCCGGTGC
CGGCAAGGACGTGAAGAGCGCCGGCGAGAAGGTCGAAGACGCCGCCAAGAACTGA

Antitoxin


Download         Length: 76 a.a.        Molecular weight: 8442.46 Da        Isoelectric Point: 5.6908

>AT166648 WP_138288229.1 NZ_CP058350:c2072132-2071905 [Rhizobium sp. ADMK78]
MATPVGHRVQKRRESLRAQGLRPVQIWLPDTRRPGFAEECARQARLTAEADRRDPGLHELLDDALADLDLAEDNG

Download         Length: 228 bp

>AT166648 NZ_CP074365:c4367668-4367516 [Xanthomonas translucens]
ATGAAGCGACTGTTCACCTTGACGATGCTGACCCTGTTTTGTGCAGGCATGCTGACCGGCTGCAACACCATGGCCGGCGC
CGGTAAGGACATGCAGAAGGCCGGCGATAAGGTGGAAACCAAGGCCGACGACTGTAAAGACGGCAAGTGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References