Detailed information of TA system TA166647

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): BrnTA/BrnT-BrnA
• Location: 1997301..1997857
• Replicon: chromosome
• Accession: NZ_CP058350
• Organism: Rhizobium sp. ADMK78

Toxin (Protein)

• Gene name: brnT
• Uniprot ID: -
• Locus tag: FE840_RS09590
• Protein ID: WP_138288306.1
• Coordinates: 1997609..1997857 (-)
• Length: 83 a.a.

Antitoxin (Protein)

• Gene name: brnA
• Uniprot ID: -
• Locus tag: FE840_RS09585
• Protein ID: WP_138288307.1
• Coordinates: 1997301..1997612 (-)
• Length: 104 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
FE840_RS09550	1992412..1993143	+	732	WP_138288314.1	thioredoxin family protein	-
FE840_RS09555	1993156..1993644	+	489	WP_138288313.1	DUF1579 domain-containing protein	-
FE840_RS09560	1993674..1994450	+	777	WP_138288312.1	VOC family protein	-
FE840_RS09565	1994509..1994745	-	237	WP_138288311.1	hypothetical protein	-
FE840_RS09570	1994863..1995102	-	240	WP_138288310.1	30S ribosomal protein S21	-
FE840_RS09575	1995412..1995621	-	210	WP_138288309.1	cold-shock protein	-
FE840_RS09580	1996189..1997238	+	1050	WP_138288308.1	fatty acid desaturase	-
FE840_RS09585	1997301..1997612	-	312	WP_138288307.1	BrnA antitoxin family protein	Antitoxin
FE840_RS09590	1997609..1997857	-	249	WP_138288306.1	BrnT family toxin	Toxin
FE840_RS09595	1997918..1998238	-	321	WP_138288305.1	YnfA family protein	-
FE840_RS09600	1998288..1999094	-	807	WP_138288304.1	EAL domain-containing protein	-
FE840_RS09605	1999795..2000196	+	402	WP_138288303.1	hypothetical protein	-
FE840_RS09610	2000302..2000775	+	474	WP_138288302.1	hypothetical protein	-
FE840_RS09615	2000894..2001133	+	240	WP_138288301.1	hypothetical protein	-
FE840_RS09620	2001223..2002788	-	1566	WP_138288300.1	DUF853 domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Ribonuclease toxin, BrnT, of type II toxin-antitoxin system (5-78)

Antitoxin

• BrnA antitoxin of type II toxin-antitoxin system (28-101)

Sequences

Toxin

Protein

• Length: 83 a.a.
• Molecular weight: 9136.64 Da
• Isoelectric Point: 10.0800

>T166647 WP_138288306.1 NZ_CP058350:c1997857-1997609 [Rhizobium sp. ADMK78]
MIIVWDEPKRLQNLAKHGLDFAELDESFFVDASIRAAKSGRTIAIGELNGRIVVAVVYTPLGREALSIISMRPASRRERS
LI

Nucleotide

• Length: 249 bp

>T166647 NZ_CP074365:3499427-3499684 [Xanthomonas translucens]
GTGACGCTTCAGTTCTCGGACAATGCCTGGGAGGACTACCTCTATTGGCAGCAGACCGACAAAAAGATGCTCAAGCGCAT
CAACGACCTGATCAAAGCCATCCAACACGATCCCTTCCAAGGCGTCGGCAAGCCAGAACCGCTGCGCCATGCCTTGGCCG
GCTATTGGTCGCGGCGGATCAACGACGCACACCGCATCGTGTACAAGGTCGAGGCGGGCGTCCTGCTGATCGCGCAGGTG
CGCTACCACTACGTGTAG

Antitoxin

Protein

• Length: 104 a.a.
• Molecular weight: 11688.19 Da
• Isoelectric Point: 4.6883

>AT166647 WP_138288307.1 NZ_CP058350:c1997612-1997301 [Rhizobium sp. ADMK78]
MSGKFSSKRPLTDEEEAEIQAMIAADPDNPEVTDEELKEFRPFREVFPDLAEAIDRRLGRPKAESPKKAISIRLDQEVID
RFKATGDGWQSRMNEALRKAVGL

Nucleotide

• Length: 312 bp

>AT166647 NZ_CP074365:3499179-3499430 [Xanthomonas translucens]
ATGGACACCATCACCTATAGCGCTGCACGCGCCGCCCTCGCGGACACCATGGAGCGTGTCGTCAACAATCACGAGCCGGT
GATCATCACCCGCAGCCGCGAGCAATCCGTGGTCATGTTGTCGCTGGAGGACTACAAGGCGATGGAGGAAACCGCGTACC
TGCTGCGCAGCCCGAAGAGCGCGCAGCGCCTGCTGGAATCCATCGCGCAGCTCGAAGCCGGTCGCGGCAAGGCACGGGAT
CTGGCCGAGTGA