166646

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) hipBA/HipA-couple_hipB
Location 1670713..1672196 Replicon chromosome
Accession NZ_CP058350
Organism Rhizobium sp. ADMK78

Toxin (Protein)


Gene name HipA1 Uniprot ID -
Locus tag FE840_RS07875 Protein ID WP_138285400.1
Coordinates 1670713..1671975 (-) Length 421 a.a.

Antitoxin (Protein)


Gene name HipB1 Uniprot ID -
Locus tag FE840_RS07880 Protein ID WP_171033630.1
Coordinates 1671972..1672196 (-) Length 75 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FE840_RS07850 1665875..1666366 + 492 WP_138285405.1 hypothetical protein -
FE840_RS07855 1666497..1667636 + 1140 WP_138285404.1 hypothetical protein -
FE840_RS07860 1668655..1668993 + 339 WP_138285403.1 DUF2293 domain-containing protein -
FE840_RS07865 1668983..1669387 + 405 WP_138285402.1 hypothetical protein -
FE840_RS07870 1670161..1670367 - 207 WP_138285401.1 hypothetical protein -
FE840_RS07875 1670713..1671975 - 1263 WP_138285400.1 type II toxin-antitoxin system HipA family toxin Toxin
FE840_RS07880 1671972..1672196 - 225 WP_171033630.1 helix-turn-helix domain-containing protein Antitoxin
FE840_RS07890 1672822..1674393 + 1572 WP_138285399.1 Ppx/GppA family phosphatase -
FE840_RS07895 1674397..1675164 + 768 WP_138285398.1 RlmE family RNA methyltransferase -
FE840_RS07900 1675178..1675561 + 384 WP_138285397.1 VOC family protein -
FE840_RS07905 1675588..1676994 - 1407 WP_138285396.1 DHA2 family efflux MFS transporter permease subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HipA, N-terminal subdomain 1

(5-102)

Antitoxin

Cro/C1-type helix-turn-helix domain

(11-65)


Sequences

Toxin        


Download         Length: 421 a.a.        Molecular weight: 45958.02 Da        Isoelectric Point: 5.5538

>T166646 WP_138285400.1 NZ_CP058350:c1671975-1670713 [Rhizobium sp. ADMK78]
MSRVLDVYLKDRKAGELKQDSDAALTFTYDSNYLANDPVALSMSLPVREEPFLDRIARPFFSGLLPDEGARRRLAAALGI
SSANAFGLLEVIGGECAGALSLVPPGQLPPASTTDDAEALDEKRLEEILSLLRQRPLLGGEGDVRLSLAGAQDKLAVTIL
NGQILLPRGGRPTTHILKPFIEGLDGTVENEVFCMSLGRRLGLDVPAVSKGTAGKIDYFLVERYDRLTLEDGRIERLHQE
DVCQALSVPPELKYEEEGGPGISECLQLIRQTTAKPAAETLRFQRMLMFHYLIGNADAHAKNYALIYRGKVPDLAPMYDA
ICTAAYPRLSKKMAMALGGRSLPDTIQMEHWASLVPSNKGATRMLAGELMRMADAIGPEADTLMEEMSETGSAHPILKTV
RKIIDTRCTLIRRALEKTNL

Download         Length: 1263 bp

>T166646 NZ_CP074365:3499179-3499430 [Xanthomonas translucens]
ATGGACACCATCACCTATAGCGCTGCACGCGCCGCCCTCGCGGACACCATGGAGCGTGTCGTCAACAATCACGAGCCGGT
GATCATCACCCGCAGCCGCGAGCAATCCGTGGTCATGTTGTCGCTGGAGGACTACAAGGCGATGGAGGAAACCGCGTACC
TGCTGCGCAGCCCGAAGAGCGCGCAGCGCCTGCTGGAATCCATCGCGCAGCTCGAAGCCGGTCGCGGCAAGGCACGGGAT
CTGGCCGAGTGA

Antitoxin


Download         Length: 75 a.a.        Molecular weight: 7950.13 Da        Isoelectric Point: 9.5008

>AT166646 WP_171033630.1 NZ_CP058350:c1672196-1671972 [Rhizobium sp. ADMK78]
MWTISDSVALGQLIHAERKRQQLTQEQLAGVAGVGVRFVRELESGKESCRVGLALTVLQTLGLTVNITNRGASS

Download         Length: 225 bp

>AT166646 NZ_CP074365:3499427-3499684 [Xanthomonas translucens]
GTGACGCTTCAGTTCTCGGACAATGCCTGGGAGGACTACCTCTATTGGCAGCAGACCGACAAAAAGATGCTCAAGCGCAT
CAACGACCTGATCAAAGCCATCCAACACGATCCCTTCCAAGGCGTCGGCAAGCCAGAACCGCTGCGCCATGCCTTGGCCG
GCTATTGGTCGCGGCGGATCAACGACGCACACCGCATCGTGTACAAGGTCGAGGCGGGCGTCCTGCTGATCGCGCAGGTG
CGCTACCACTACGTGTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References