Detailed information of TA system TA166645

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): PP_4151-4152/excise(antitoxin)
• Location: 1498613..1499630
• Replicon: chromosome
• Accession: NZ_CP058350
• Organism: Rhizobium sp. ADMK78

Toxin (Protein)

• Gene name: PP_4152
• Uniprot ID: -
• Locus tag: FE840_RS07095
• Protein ID: WP_210271789.1
• Coordinates: 1499055..1499630 (+)
• Length: 192 a.a.

Antitoxin (Protein)

• Gene name: PP_4151
• Uniprot ID: -
• Locus tag: FE840_RS07090
• Protein ID: WP_138285542.1
• Coordinates: 1498613..1499059 (+)
• Length: 149 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
FE840_RS07050	1494072..1494509	+	438	WP_138285548.1	DUF2948 family protein	-
FE840_RS07055	1494566..1495864	+	1299	WP_138285547.1	histidinol dehydrogenase	-
FE840_RS07060	1495872..1496345	+	474	WP_138285546.1	UPF0262 family protein	-
FE840_RS07065	1496350..1496805	+	456	WP_138285545.1	low molecular weight phosphatase family protein	-
FE840_RS07070	1496954..1497172	+	219	WP_004435948.1	translation initiation factor IF-1	-
FE840_RS07075	1497196..1497816	+	621	WP_138285544.1	Maf-like protein	-
FE840_RS07080	1497821..1498033	+	213	WP_138285543.1	DNA gyrase inhibitor YacG	-
FE840_RS07090	1498613..1499059	+	447	WP_138285542.1	helix-turn-helix domain-containing protein	Antitoxin
FE840_RS07095	1499055..1499630	+	576	WP_210271789.1	PIN domain-containing protein	Toxin
FE840_RS07100	1499896..1500957	+	1062	WP_138285540.1	glycoside hydrolase family 25 protein	-
FE840_RS07105	1501059..1501310	-	252	WP_138285539.1	hypothetical protein	-
FE840_RS07110	1501499..1503355	+	1857	WP_171033639.1	malto-oligosyltrehalose trehalohydrolase	-
FE840_RS07115	1503460..1503708	+	249	WP_138285537.1	hypothetical protein	-
FE840_RS07120	1503856..1504131	-	276	WP_138285536.1	BON domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• PIN domain (8-115)

Antitoxin

• SinI-like, DNA-binding domain (78-122)

Sequences

Toxin

Protein

• Length: 192 a.a.
• Molecular weight: 21597.79 Da
• Isoelectric Point: 5.6358

>T166645 WP_210271789.1 NZ_CP058350:1499055-1499630 [Rhizobium sp. ADMK78]
IKKSRYTVVLDACVLYPAPLRDFLMELAAAGLFRAKWSEQIHDEWIRNVLKDRHDLTAEQLGRTKDLMNAAVPDCMVEGY
EDLVPSVTLPDMDDRHVLAAAIASSSDAIVTFNLKDFPKATVAKYNIEVLHPDDFIFHQFGLNNAGVIIAAQRCRARLRN
PPKTSEEYLQTLERQSLPKTVAELQEYLSVL

Nucleotide

• Length: 576 bp

>T166645 NZ_CP074365:c3497081-3496932 [Xanthomonas translucens]
TTGGACGACGAGACCTACGCCAAGTTACAGGTGTTGCTGCAGGAAAATCTAGAAGTCGGAGATCTGATCGAAGGAACCGG
TGGCCTGCGCAAGGTGCGCGTCGCCGCGAAAGGGCATGGCAAGCGAGGTGGCGCCCGTGTCATCTATTAA

Antitoxin

Protein

• Length: 149 a.a.
• Molecular weight: 16732.16 Da
• Isoelectric Point: 6.3419

>AT166645 WP_138285542.1 NZ_CP058350:1498613-1499059 [Rhizobium sp. ADMK78]
MSQLLERPILPTADDTELAAQASRYISRAKHEGAELRVQVDGGEPLKLPRAVSELLYHLLTEMAQGNAVTVIPVHAELTT
QEAADQLNVSRPYLIKLLEEGKIPFHMVGSHRRIKFSDLDNFRRKAEDERKRLMDELAEQAQKLGMGY

Nucleotide

• Length: 447 bp

>AT166645 NZ_CP074365:c3496812-3496630 [Xanthomonas translucens]
ATGAGCAAGTTCTTCGAAGCGCTGATGGAAAGCGTGCAGCAGATGGACGAGATCGTCCGTGGCGAGCGTGCTCCTTCGCG
CGAGTTCCATGTCGATGCGATCCAGGTCAAGCAAGTGCGTCTACCGGCCTCTCCCAGTCTAAGAGCGGCTAACAAAACTC
TGGAAGTCGCCGTAGGCAGATGA