Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PP_4151-4152/excise(antitoxin)
Location 1498613..1499630 Replicon chromosome
Accession NZ_CP058350
Organism Rhizobium sp. ADMK78

Toxin (Protein)


Gene name PP_4152 Uniprot ID -
Locus tag FE840_RS07095 Protein ID WP_210271789.1
Coordinates 1499055..1499630 (+) Length 192 a.a.

Antitoxin (Protein)


Gene name PP_4151 Uniprot ID -
Locus tag FE840_RS07090 Protein ID WP_138285542.1
Coordinates 1498613..1499059 (+) Length 149 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FE840_RS07050 1494072..1494509 + 438 WP_138285548.1 DUF2948 family protein -
FE840_RS07055 1494566..1495864 + 1299 WP_138285547.1 histidinol dehydrogenase -
FE840_RS07060 1495872..1496345 + 474 WP_138285546.1 UPF0262 family protein -
FE840_RS07065 1496350..1496805 + 456 WP_138285545.1 low molecular weight phosphatase family protein -
FE840_RS07070 1496954..1497172 + 219 WP_004435948.1 translation initiation factor IF-1 -
FE840_RS07075 1497196..1497816 + 621 WP_138285544.1 Maf-like protein -
FE840_RS07080 1497821..1498033 + 213 WP_138285543.1 DNA gyrase inhibitor YacG -
FE840_RS07090 1498613..1499059 + 447 WP_138285542.1 helix-turn-helix domain-containing protein Antitoxin
FE840_RS07095 1499055..1499630 + 576 WP_210271789.1 PIN domain-containing protein Toxin
FE840_RS07100 1499896..1500957 + 1062 WP_138285540.1 glycoside hydrolase family 25 protein -
FE840_RS07105 1501059..1501310 - 252 WP_138285539.1 hypothetical protein -
FE840_RS07110 1501499..1503355 + 1857 WP_171033639.1 malto-oligosyltrehalose trehalohydrolase -
FE840_RS07115 1503460..1503708 + 249 WP_138285537.1 hypothetical protein -
FE840_RS07120 1503856..1504131 - 276 WP_138285536.1 BON domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(8-115)

Antitoxin

SinI-like, DNA-binding domain

(78-122)


Sequences

Toxin        


Download         Length: 192 a.a.        Molecular weight: 21597.79 Da        Isoelectric Point: 5.6358

>T166645 WP_210271789.1 NZ_CP058350:1499055-1499630 [Rhizobium sp. ADMK78]
IKKSRYTVVLDACVLYPAPLRDFLMELAAAGLFRAKWSEQIHDEWIRNVLKDRHDLTAEQLGRTKDLMNAAVPDCMVEGY
EDLVPSVTLPDMDDRHVLAAAIASSSDAIVTFNLKDFPKATVAKYNIEVLHPDDFIFHQFGLNNAGVIIAAQRCRARLRN
PPKTSEEYLQTLERQSLPKTVAELQEYLSVL

Download         Length: 576 bp

>T166645 NZ_CP074365:c3497081-3496932 [Xanthomonas translucens]
TTGGACGACGAGACCTACGCCAAGTTACAGGTGTTGCTGCAGGAAAATCTAGAAGTCGGAGATCTGATCGAAGGAACCGG
TGGCCTGCGCAAGGTGCGCGTCGCCGCGAAAGGGCATGGCAAGCGAGGTGGCGCCCGTGTCATCTATTAA

Antitoxin


Download         Length: 149 a.a.        Molecular weight: 16732.16 Da        Isoelectric Point: 6.3419

>AT166645 WP_138285542.1 NZ_CP058350:1498613-1499059 [Rhizobium sp. ADMK78]
MSQLLERPILPTADDTELAAQASRYISRAKHEGAELRVQVDGGEPLKLPRAVSELLYHLLTEMAQGNAVTVIPVHAELTT
QEAADQLNVSRPYLIKLLEEGKIPFHMVGSHRRIKFSDLDNFRRKAEDERKRLMDELAEQAQKLGMGY

Download         Length: 447 bp

>AT166645 NZ_CP074365:c3496812-3496630 [Xanthomonas translucens]
ATGAGCAAGTTCTTCGAAGCGCTGATGGAAAGCGTGCAGCAGATGGACGAGATCGTCCGTGGCGAGCGTGCTCCTTCGCG
CGAGTTCCATGTCGATGCGATCCAGGTCAAGCAAGTGCGTCTACCGGCCTCTCCCAGTCTAAGAGCGGCTAACAAAACTC
TGGAAGTCGCCGTAGGCAGATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References