166643

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/PRK09812-MazE
Location 376822..377459 Replicon chromosome
Accession NZ_CP058350
Organism Rhizobium sp. ADMK78

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag FE840_RS01845 Protein ID WP_138288475.1
Coordinates 376822..377193 (-) Length 124 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag FE840_RS01850 Protein ID WP_138288476.1
Coordinates 377193..377459 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FE840_RS01815 372072..372926 - 855 WP_138288470.1 aromatic ring-hydroxylating dioxygenase subunit alpha -
FE840_RS01820 373067..373339 + 273 WP_171033776.1 hypothetical protein -
FE840_RS01825 373332..374015 + 684 WP_138288471.1 Rieske (2Fe-2S) protein -
FE840_RS01830 374015..374647 + 633 WP_138288472.1 glutathione S-transferase family protein -
FE840_RS01835 374720..375673 + 954 WP_171033766.1 D-2-hydroxyacid dehydrogenase -
FE840_RS01840 375743..376816 + 1074 WP_138288474.1 enoyl-CoA hydratase/isomerase family protein -
FE840_RS01845 376822..377193 - 372 WP_138288475.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
FE840_RS01850 377193..377459 - 267 WP_138288476.1 PbsX family transcriptional regulator Antitoxin
FE840_RS01855 377514..378922 - 1409 Protein_362 XRE family transcriptional regulator -
FE840_RS01860 379057..380589 + 1533 WP_138288478.1 acyl-CoA carboxylase subunit beta -
FE840_RS01865 380696..381607 + 912 WP_138288479.1 glutathione-dependent disulfide-bond oxidoreductase -
FE840_RS01870 381617..381994 + 378 WP_138288480.1 hypothetical protein -
FE840_RS01875 381999..382412 + 414 WP_138288481.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(8-113)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 124 a.a.        Molecular weight: 13349.34 Da        Isoelectric Point: 7.9183

>T166643 WP_138288475.1 NZ_CP058350:c377193-376822 [Rhizobium sp. ADMK78]
MVRSGVPRRGDVYWIDPNPVAGREMKNRHRFVVITPHEINVFGVCMTVPVTTGGAFTRDIGLAVPIHGHDTTGIAVCNQV
RSFDIAARVQQRSASFIETLDKATVDEIVARVVSAIDPLPGSV

Download         Length: 372 bp

>T166643 NZ_CP074365:c1167461-1167168 [Xanthomonas translucens]
ATGACCGAAAACCTGACCACCTACGATCCTGCCGAGGATCTGAACTCCGACCAGGCGATTGCCGATTTCATGGCGGGCGC
CTTTGCGACCAACGACACCGGCTTCATCGCCCATGCCCTCGGCATCGTCGCCCGTGCCAAGGGCATGACCCAGATCGCAC
GACAAACCGGCCTGTCCCGGGAGCAGCTCTACCGCTCCTTCAGCGAGGACGGAAATCCGACGCTGCGCACTACCCTGGCC
GTCATGAAGGCGCTCGGGATCGAACTGACGGCCAAAGCCGCCGTCACGCATTGA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 9185.71 Da        Isoelectric Point: 4.7063

>AT166643 WP_138288476.1 NZ_CP058350:c377459-377193 [Rhizobium sp. ADMK78]
MTVTTKVRKQGGAAVVTIPPALLKLMAVEVGDQLSLDVQNGELVAKPLRAGVKRYTLAELLVGAEELAQLNASLAETMDG
DAIGREIG

Download         Length: 267 bp

>AT166643 NZ_CP074365:c1167760-1167464 [Xanthomonas translucens]
GTGATCGAACTCAAACAGACCGAGACGTTCCGCAAGTGGCGCACGAAGCTGAAGGACGAGCGCGCTCGCACTGCGATTGC
CTTGCGCTTGACCCGACTTGCCTATGGCCATGCCGGCGATACGGAAGCTGTCGGGCAAGGCATCAGCGAGCTGCGTATCC
ACCATGGCCCCGGATATCGGGTGTATTTCCAGCGGCGCGGCGACACGATCATCGTCTTGCTCTGCGGTGGCGACAAAAGC
ACGCAGGCAAAGGACATCAAGACAGCCAAACGGCTTGCCGACGAATGGAGCGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References