Detailed information of TA system TA166642

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relB-parE/RHH(antitoxin)
• Location: 360105..360658
• Replicon: chromosome
• Accession: NZ_CP058350
• Organism: Rhizobium sp. ADMK78

Toxin (Protein)

• Gene name: parE
• Uniprot ID: -
• Locus tag: FE840_RS01725
• Protein ID: WP_138288454.1
• Coordinates: 360365..360658 (+)
• Length: 98 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: FE840_RS01720
• Protein ID: WP_138288453.1
• Coordinates: 360105..360377 (+)
• Length: 91 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
FE840_RS01695	355226..356287	-	1062	WP_138288449.1	dipeptidase	-
FE840_RS01700	356449..357285	-	837	WP_138288450.1	amidohydrolase	-
FE840_RS01705	357486..358220	+	735	WP_138288451.1	SDR family oxidoreductase	-
FE840_RS01710	358345..359187	+	843	WP_138288452.1	fumarylacetoacetate hydrolase family protein	-
FE840_RS01715	359297..359899	-	603	WP_138288620.1	AAA family ATPase	-
FE840_RS01720	360105..360377	+	273	WP_138288453.1	CopG family ribbon-helix-helix protein	Antitoxin
FE840_RS01725	360365..360658	+	294	WP_138288454.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
FE840_RS01730	360749..362251	-	1503	WP_138288455.1	NAD(P)(+) transhydrogenase (Re/Si-specific) subunit beta	-
FE840_RS01735	362267..363838	-	1572	WP_138288456.1	Re/Si-specific NAD(P)(+) transhydrogenase subunit alpha	-
FE840_RS01740	364107..364271	+	165	WP_138288457.1	DUF1328 domain-containing protein	-
FE840_RS01745	364339..365094	-	756	WP_138288458.1	Crp/Fnr family transcriptional regulator	-
FE840_RS01750	365220..365609	+	390	WP_138288459.1	response regulator transcription factor	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-95)

Antitoxin

• Ribbon-helix-helix protein, CopG (3-40)

Sequences

Toxin

Protein

• Length: 98 a.a.
• Molecular weight: 10896.61 Da
• Isoelectric Point: 10.0618

>T166642 WP_138288454.1 NZ_CP058350:360365-360658 [Rhizobium sp. ADMK78]
VPRVVVTEGAAIGLERCRRFLQAKSLDAAEKAAKEIKRQFTLLASNPKRGRPLPRFPDLRELTIGFGAAGYVALYRYDEP
EDVVHILAFKHQKEAGY

Nucleotide

• Length: 294 bp

>T166642 NZ_CP074365:c535230-534937 [Xanthomonas translucens]
TTGGGAAGTTATCGCCTGTTCGGCACGAATGAAAAGGGTGAAAAAGTGATGGTTGCCAGCGTCGCCGATGGCGAACTCAG
CATTCACGACCCCCAGTTGTATGAGAGCATTACAGCTCCCGAGGACTTCAACTCGGGTGACAAAGGAGAACAGGTAATCG
ACACAGCGCTGATTGACCGTTTGAGCAACAGCATCGATGATCCAAAGCGTGCAACGGATGCACGTGCCGCCCTGGAGAAA
TGCAAGGGAATGACGTGGTCAAATGCTCTAGCGGCACACAGTTCATTGATCTGA

Antitoxin

Protein

• Length: 91 a.a.
• Molecular weight: 10445.57 Da
• Isoelectric Point: 4.5396

>AT166642 WP_138288453.1 NZ_CP058350:360105-360377 [Rhizobium sp. ADMK78]
MATSLKIDDALKERVQQLANERKRSAHGLMLEAIEQYVEREEARESFTREALASWTAYKETGRHLTLDEVNDWLETWGSA
DEKPVPECHE

Nucleotide

• Length: 273 bp

>AT166642 NZ_CP074365:c534923-534627 [Xanthomonas translucens]
ATGACCCACTTAAAAGGCGCAGATGCACTTGCCCTGCATAAGAAACTCAAAGAGCGCAATGCCGCATTACGCAGTGCCGA
ACTTGATTCAGCAAAGGCGCTAGCCCATGAAAGCGGCAAAGAGCGCTTCAACCTCGAAAAATTGGAGAGCATTTGCGACA
CCACTCAAGCAGGGCGCATTACCGACCCGAACGATCGTCAGGCCATTTACGAACAAATGTATTATGTCGAGCATCCCAAA
ATCAGCACCTTGCAAGAATTCGCCCGCATTGTGGTGACGATTTCCTCATGGTCTTGA