Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 3974927..3975561 Replicon chromosome
Accession NZ_CP058349
Organism Pseudomonas sp. ABC1

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag HW090_RS17555 Protein ID WP_179114731.1
Coordinates 3975157..3975561 (+) Length 135 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag HW090_RS17550 Protein ID WP_179114730.1
Coordinates 3974927..3975157 (+) Length 77 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HW090_RS17520 3970524..3971093 - 570 WP_179114724.1 DUF4339 domain-containing protein -
HW090_RS17525 3971274..3971621 + 348 WP_179114725.1 helix-turn-helix domain-containing protein -
HW090_RS17530 3972009..3972197 - 189 WP_179114726.1 hypothetical protein -
HW090_RS17535 3972214..3972711 - 498 WP_179114727.1 DNA repair protein RadC -
HW090_RS17540 3972767..3973681 - 915 WP_179114728.1 hypothetical protein -
HW090_RS17545 3973762..3974766 - 1005 WP_179114729.1 YqaJ viral recombinase family protein -
HW090_RS17550 3974927..3975157 + 231 WP_179114730.1 antitoxin Antitoxin
HW090_RS17555 3975157..3975561 + 405 WP_179114731.1 tRNA(fMet)-specific endonuclease VapC Toxin
HW090_RS17560 3975635..3976603 - 969 WP_179114732.1 DUF932 domain-containing protein -
HW090_RS17565 3976721..3976987 + 267 WP_179114733.1 hypothetical protein -
HW090_RS17570 3977138..3977844 - 707 Protein_3442 transposase -
HW090_RS17575 3977916..3978104 - 189 WP_179114959.1 formate dehydrogenase subunit delta -
HW090_RS17580 3978247..3978566 - 320 Protein_3444 hypothetical protein -
HW090_RS17585 3978848..3979723 - 876 WP_179114734.1 WYL domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 3952313..3993524 41211
- flank IS/Tn - - 3977536..3977844 308


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(5-124)

Antitoxin

SpoVT-AbrB domain

(7-35)


Sequences

Toxin        


Download         Length: 135 a.a.        Molecular weight: 15097.26 Da        Isoelectric Point: 7.2782

>T166640 WP_179114731.1 NZ_CP058349:3975157-3975561 [Pseudomonas sp. ABC1]
MLKFMLDTNICIFTIKNRPEQVRETFKRHSGQLSISTITLMELIYGAEKSSNPERNLADVEGFAARLDVLPYDSQAATHS
GQLRSELARVGKPIGPYDQMIAGHARSQGLILVTNNLREFERVPGLRVEDWVNP

Download         Length: 405 bp

>T166640 NZ_CP074364:3395972-3396229 [Xanthomonas translucens pv. cerealis]
GTGACGGTTCAGTTCTCGGACAATGCCTGGGAGGACGACCTCTACTGGCAGCAGACCGACAAGAAGATGCTCAAACGCAT
CAACGACCTGATCAAAGCCATTCAACGCGATCCCTTCCAAGGCGTCGGCAAGCCAGAACCGCTGCGCCATGCCTTGGCCG
GCTATTGGTCGCGGCGCATCAACGACGAACATCGCATCGTGTACAAGGTCGAGGCTGGCGTCCTGCTGATCGCGCAGGTG
CGCTACCACTACGTGTAG

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 8450.38 Da        Isoelectric Point: 4.2683

>AT166640 WP_179114730.1 NZ_CP058349:3974927-3975157 [Pseudomonas sp. ABC1]
MEQGAVFQSNRSQAVRLPKAVALPEDVKRVDVVVVGRTRIITPAGEAWDSWFDGEGVTADYMADREQPADQERDAF

Download         Length: 231 bp

>AT166640 NZ_CP074364:3395724-3395975 [Xanthomonas translucens pv. cerealis]
ATGGACACCATCACCTATAGCGCTGCACGCGCTGCCCTTGCGGACACCATGGAGCGCGTGGTCAACAACCACGAGCCGGT
GATCATCACCCGCAGCCGCGAGCAATCCGTGGTCATGCTGTCGCTGGAGGACTACAAGGCGATGGAGGAAACCTCCTACC
TGCTCCGCAGTCCGAAGAGCGCGCAGCGCCTGCTGGAATCCATCGCCCAGCTCGAGGCCGGTCGCGGCAAGGCACGGGAC
CTGGCCGAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References