Detailed information of TA system TA166639

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): tad-ata/COG5606-COG4679
• Location: 1300588..1301258
• Replicon: chromosome
• Accession: NZ_CP058349
• Organism: Pseudomonas sp. ABC1

Toxin (Protein)

• Gene name: tad
• Uniprot ID: -
• Locus tag: HW090_RS05685
• Protein ID: WP_179112566.1
• Coordinates: 1300588..1300941 (+)
• Length: 118 a.a.

Antitoxin (Protein)

• Gene name: ata
• Uniprot ID: -
• Locus tag: HW090_RS05690
• Protein ID: WP_179112567.1
• Coordinates: 1300938..1301258 (+)
• Length: 107 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
HW090_RS05675	1297668..1298924	+	1257	WP_179112564.1	MgtC/SapB family protein	-
HW090_RS05680	1299000..1300451	-	1452	WP_179112565.1	DNA recombination protein RmuC	-
HW090_RS05685	1300588..1300941	+	354	WP_179112566.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
HW090_RS05690	1300938..1301258	+	321	WP_179112567.1	helix-turn-helix domain-containing protein	Antitoxin
HW090_RS05695	1301289..1302008	-	720	WP_179112568.1	adenosylcobinamide-GDP ribazoletransferase	-
HW090_RS05700	1301993..1302586	-	594	WP_179112569.1	alpha-ribazole phosphatase family protein	-
HW090_RS05705	1302583..1303626	-	1044	WP_179112570.1	nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase	-
HW090_RS05710	1303623..1304144	-	522	WP_179112571.1	bifunctional adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase	-
HW090_RS05715	1304141..1305598	-	1458	WP_179112572.1	cobyric acid synthase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin HigB-like (13-105)

Antitoxin

• Cro/C1-type helix-turn-helix domain (32-88)

Sequences

Toxin

Protein

• Length: 118 a.a.
• Molecular weight: 12977.97 Da
• Isoelectric Point: 9.3409

>T166639 WP_179112566.1 NZ_CP058349:1300588-1300941 [Pseudomonas sp. ABC1]
MMKTLYWIGSSRKELGKMPEDVQDVFGYALHLAQEGSKHPQAKPLKGFSGAGVLEVVEDFAGDTYRAVYTVRFAKVVYAL
HCFQKKSNKGIETPQHDIELIKARLIAAATHANGVEK

Nucleotide

• Length: 354 bp

>T166639 NZ_CP074364:3395724-3395975 [Xanthomonas translucens pv. cerealis]
ATGGACACCATCACCTATAGCGCTGCACGCGCTGCCCTTGCGGACACCATGGAGCGCGTGGTCAACAACCACGAGCCGGT
GATCATCACCCGCAGCCGCGAGCAATCCGTGGTCATGCTGTCGCTGGAGGACTACAAGGCGATGGAGGAAACCTCCTACC
TGCTCCGCAGTCCGAAGAGCGCGCAGCGCCTGCTGGAATCCATCGCCCAGCTCGAGGCCGGTCGCGGCAAGGCACGGGAC
CTGGCCGAGTGA

Antitoxin

Protein

• Length: 107 a.a.
• Molecular weight: 11741.67 Da
• Isoelectric Point: 10.3979

>AT166639 WP_179112567.1 NZ_CP058349:1300938-1301258 [Pseudomonas sp. ABC1]
MTDIEESSGNPYADIGQTNASEMQVKARLATKIGEIIKSRRLTQLQAAEILGLPQPKVSDMLRGKFRGISEAKMIDCLSR
LGRDVQILIKTAPRSRKEGRVEVIFA

Nucleotide

• Length: 321 bp

>AT166639 NZ_CP074364:3395972-3396229 [Xanthomonas translucens pv. cerealis]
GTGACGGTTCAGTTCTCGGACAATGCCTGGGAGGACGACCTCTACTGGCAGCAGACCGACAAGAAGATGCTCAAACGCAT
CAACGACCTGATCAAAGCCATTCAACGCGATCCCTTCCAAGGCGTCGGCAAGCCAGAACCGCTGCGCCATGCCTTGGCCG
GCTATTGGTCGCGGCGCATCAACGACGAACATCGCATCGTGTACAAGGTCGAGGCTGGCGTCCTGCTGATCGCGCAGGTG
CGCTACCACTACGTGTAG