Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3334131..3334276 Replicon chromosome
Accession NZ_CP058325
Organism Klebsiella pneumoniae subsp. pneumoniae strain LC-1825/18

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3334138..3334240 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3334131..3334276 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GLO21_RS16430 (GLO21_016435) 3329663..3331096 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
GLO21_RS16435 (GLO21_016440) 3331212..3331451 + 240 WP_002911393.1 YebV family protein -
GLO21_RS16440 (GLO21_016445) 3331549..3331740 + 192 WP_002911395.1 YebW family protein -
GLO21_RS16445 (GLO21_016450) 3331737..3332390 - 654 WP_002911396.1 protein-serine/threonine phosphatase -
GLO21_RS16450 (GLO21_016455) 3332547..3333515 + 969 WP_004151446.1 VirK/YbjX family protein -
GLO21_RS16455 (GLO21_016460) 3333620..3333763 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 3334131..3334276 + 146 - - Antitoxin
- 3334138..3334240 - 103 - - Toxin
GLO21_RS16460 (GLO21_016465) 3334399..3334737 - 339 WP_002911404.1 YebY family protein -
GLO21_RS16465 (GLO21_016470) 3334754..3335623 - 870 WP_004151447.1 copper homeostasis membrane protein CopD -
GLO21_RS16470 (GLO21_016475) 3335627..3336001 - 375 WP_004151448.1 CopC domain-containing protein YobA -
GLO21_RS16475 (GLO21_016480) 3336114..3336344 + 231 WP_002911406.1 DNA polymerase III subunit theta -
GLO21_RS16480 (GLO21_016485) 3336423..3337082 + 660 WP_002911407.1 exodeoxyribonuclease X -
GLO21_RS16485 (GLO21_016490) 3337086..3339146 - 2061 WP_004151449.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T166558 NZ_CP058325:c3334240-3334138 [Klebsiella pneumoniae subsp. pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT166558 NZ_CP058325:3334131-3334276 [Klebsiella pneumoniae subsp. pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References