Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | vapBC/PIN-PHD |
| Location | 5838833..5839576 | Replicon | chromosome |
| Accession | NZ_CP058322 | ||
| Organism | Micromonospora carbonacea strain aurantiaca | ||
Toxin (Protein)
| Gene name | vapC | Uniprot ID | - |
| Locus tag | HXZ27_RS24185 | Protein ID | WP_178066047.1 |
| Coordinates | 5838833..5839207 (+) | Length | 125 a.a. |
Antitoxin (Protein)
| Gene name | vapB | Uniprot ID | - |
| Locus tag | HXZ27_RS24190 | Protein ID | WP_181019396.1 |
| Coordinates | 5839298..5839576 (+) | Length | 93 a.a. |
Genomic Context
Location: 5834413..5835462 (1050 bp)
Type: Others
Protein ID: WP_083302629.1
Type: Others
Protein ID: WP_083302629.1
Location: 5835510..5836535 (1026 bp)
Type: Others
Protein ID: WP_178067725.1
Type: Others
Protein ID: WP_178067725.1
Location: 5836520..5837410 (891 bp)
Type: Others
Protein ID: WP_178066045.1
Type: Others
Protein ID: WP_178066045.1
Location: 5838582..5838836 (255 bp)
Type: Others
Protein ID: WP_178067727.1
Type: Others
Protein ID: WP_178067727.1
Location: 5838833..5839207 (375 bp)
Type: Toxin
Protein ID: WP_178066047.1
Type: Toxin
Protein ID: WP_178066047.1
Location: 5839298..5839576 (279 bp)
Type: Antitoxin
Protein ID: WP_181019396.1
Type: Antitoxin
Protein ID: WP_181019396.1
Location: 5839573..5839983 (411 bp)
Type: Others
Protein ID: WP_178066049.1
Type: Others
Protein ID: WP_178066049.1
Location: 5837340..5838431 (1092 bp)
Type: Others
Protein ID: WP_178066046.1
Type: Others
Protein ID: WP_178066046.1
Location: 5840090..5841145 (1056 bp)
Type: Others
Protein ID: WP_178066050.1
Type: Others
Protein ID: WP_178066050.1
Location: 5841147..5842847 (1701 bp)
Type: Others
Protein ID: WP_178067729.1
Type: Others
Protein ID: WP_178067729.1
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Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| HXZ27_RS24160 | 5834413..5835462 | + | 1050 | WP_083302629.1 | iron chelate uptake ABC transporter family permease subunit | - |
| HXZ27_RS24165 | 5835510..5836535 | + | 1026 | WP_178067725.1 | iron chelate uptake ABC transporter family permease subunit | - |
| HXZ27_RS24170 | 5836520..5837410 | + | 891 | WP_178066045.1 | ABC transporter ATP-binding protein | - |
| HXZ27_RS24175 | 5837340..5838431 | - | 1092 | WP_178066046.1 | hypothetical protein | - |
| HXZ27_RS24180 | 5838582..5838836 | + | 255 | WP_178067727.1 | type II toxin-antitoxin system prevent-host-death family antitoxin | - |
| HXZ27_RS24185 | 5838833..5839207 | + | 375 | WP_178066047.1 | type II toxin-antitoxin system VapC family toxin | Toxin |
| HXZ27_RS24190 | 5839298..5839576 | + | 279 | WP_181019396.1 | type II toxin-antitoxin system prevent-host-death family antitoxin | Antitoxin |
| HXZ27_RS24195 | 5839573..5839983 | + | 411 | WP_178066049.1 | type II toxin-antitoxin system VapC family toxin | - |
| HXZ27_RS24200 | 5840090..5841145 | - | 1056 | WP_178066050.1 | NADP-dependent oxidoreductase | - |
| HXZ27_RS24205 | 5841147..5842847 | - | 1701 | WP_178067729.1 | NAD(P)/FAD-dependent oxidoreductase | - |
Associated MGEs
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MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| No matching records found | |||||||
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 125 a.a. Molecular weight: 13633.78 Da Isoelectric Point: 5.4747
>T166551 WP_178066047.1 NZ_CP058322:5838833-5839207 [Micromonospora carbonacea]
MTLLLDTHVALWAITGDATLGVDFLDQLRHDPDILLSPVTLWEITIKQGAGKLVGPPDLAERVREMGFRELPVTHAHAIA
ASRLPPHHRDPFDRMLVAQAITEGLTLATRDASIALYDVDVLKV
MTLLLDTHVALWAITGDATLGVDFLDQLRHDPDILLSPVTLWEITIKQGAGKLVGPPDLAERVREMGFRELPVTHAHAIA
ASRLPPHHRDPFDRMLVAQAITEGLTLATRDASIALYDVDVLKV
Download Length: 375 bp
>T166551 NZ_CP074351:579056-579427 [Pantoea dispersa]
GTGTGGCAGGTTGAAGCAACAGATCGGTTTTGTAAATGGTTGCAGGCTCAGGATGAAGCGTTGCGTCTCGACGTGCTTGC
CGCCCTGAAGCTTCTGGCGCAGGACGGTCCGCATCTTGGCCGCCCTTTCGTTGATACCCTGATGTTATCGCGGGTGCCCA
ATATGAAAGAGCTTCGCGTGCAAAGTAAAGGTCGTCCCATCCGCAGCTTTTTTGTTTTCGATCCGCGCCGCCATGCGATT
GTGCTGTGTGCCGGCAACAAACAGGGTAAAAATCAGAAGCGTTTCTATCAGCAGATGCTTCGCATTGCCGAAACCGAATA
CCATCATCATCTGAACGCAATCGGGGAAACTCATAATGAAAACCTTGGATGA
GTGTGGCAGGTTGAAGCAACAGATCGGTTTTGTAAATGGTTGCAGGCTCAGGATGAAGCGTTGCGTCTCGACGTGCTTGC
CGCCCTGAAGCTTCTGGCGCAGGACGGTCCGCATCTTGGCCGCCCTTTCGTTGATACCCTGATGTTATCGCGGGTGCCCA
ATATGAAAGAGCTTCGCGTGCAAAGTAAAGGTCGTCCCATCCGCAGCTTTTTTGTTTTCGATCCGCGCCGCCATGCGATT
GTGCTGTGTGCCGGCAACAAACAGGGTAAAAATCAGAAGCGTTTCTATCAGCAGATGCTTCGCATTGCCGAAACCGAATA
CCATCATCATCTGAACGCAATCGGGGAAACTCATAATGAAAACCTTGGATGA
Antitoxin
Download Length: 93 a.a. Molecular weight: 9753.03 Da Isoelectric Point: 4.5859
>AT166551 WP_181019396.1 NZ_CP058322:5839298-5839576 [Micromonospora carbonacea]
MERIGVRELNQNTSQVLARVSGGETVEITDRGHPIARLVPVGDDRSMLARLVAAGRAVAPTGGGPVPLPPQLGDEDVDVA
ATLAAMRDEERW
MERIGVRELNQNTSQVLARVSGGETVEITDRGHPIARLVPVGDDRSMLARLVAAGRAVAPTGGGPVPLPPQLGDEDVDVA
ATLAAMRDEERW
Download Length: 279 bp
>AT166551 NZ_CP074351:579411-579710 [Pantoea dispersa]
ATGAAAACCTTGGATGAGATGCTGGCGGCGCTGACGCCCGAACAGCAACATCAGGTCGATGAACGCGTCAGCCAGATGCG
TCTTGAATACCAGCTTTACCAATTACGTGAGCAGATGCAGCGGACTCAGCGTCAGCAAGCGCAGGCCATGCACATTGCCC
AGTCATCTGTGGCGGCGATGGAAGCGCGTGGCGCAGAGTTAAAAATTTCCACGCTGAAGCGCTACATTGAGGCGCTGGGT
GGAGAGCTGACGCTGGGTGTAAAGATGCCGGGTGGCCAGCATGTCGACTTAATTATCTGA
ATGAAAACCTTGGATGAGATGCTGGCGGCGCTGACGCCCGAACAGCAACATCAGGTCGATGAACGCGTCAGCCAGATGCG
TCTTGAATACCAGCTTTACCAATTACGTGAGCAGATGCAGCGGACTCAGCGTCAGCAAGCGCAGGCCATGCACATTGCCC
AGTCATCTGTGGCGGCGATGGAAGCGCGTGGCGCAGAGTTAAAAATTTCCACGCTGAAGCGCTACATTGAGGCGCTGGGT
GGAGAGCTGACGCTGGGTGTAAAGATGCCGGGTGGCCAGCATGTCGACTTAATTATCTGA