Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) slvAT/RES(toxin)
Location 982291..983234 Replicon chromosome
Accession NZ_CP058321
Organism Halomonas sp. SH5A2

Toxin (Protein)


Gene name slvT Uniprot ID -
Locus tag HXW73_RS04645 Protein ID WP_186255122.1
Coordinates 982716..983234 (+) Length 173 a.a.

Antitoxin (Protein)


Gene name slvA Uniprot ID -
Locus tag HXW73_RS04640 Protein ID WP_186255121.1
Coordinates 982291..982719 (+) Length 143 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HXW73_RS04625 977687..978214 - 528 WP_186255118.1 hypothetical protein -
HXW73_RS04630 978211..978519 - 309 WP_186255119.1 nucleotidyltransferase domain-containing protein -
HXW73_RS04635 978574..982140 - 3567 WP_186255120.1 exodeoxyribonuclease V subunit gamma -
HXW73_RS04640 982291..982719 + 429 WP_186255121.1 DUF2384 domain-containing protein Antitoxin
HXW73_RS04645 982716..983234 + 519 WP_186255122.1 RES family NAD+ phosphorylase Toxin
HXW73_RS04650 983319..983633 - 315 WP_179928892.1 putative addiction module antidote protein -
HXW73_RS04655 983865..985550 + 1686 WP_186255123.1 dihydroxy-acid dehydratase -
HXW73_RS04660 985644..986825 + 1182 WP_186255124.1 chromate efflux transporter -
HXW73_RS04665 986922..987194 - 273 WP_186255125.1 XRE family transcriptional regulator -
HXW73_RS04670 987405..987920 + 516 WP_186255126.1 5-(carboxyamino)imidazole ribonucleotide mutase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RES domain

(11-167)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 173 a.a.        Molecular weight: 19243.86 Da        Isoelectric Point: 4.7222

>T166547 WP_186255122.1 NZ_CP058321:982716-983234 [Halomonas sp. SH5A2]
MIVLPALNTQAYRVHVPKWAFSPTSGAGAREHGGRLNRPGVAALYLALDDQTALAEYKQLSALMPSGLIVSYTISVTQLV
DFRNGYSMQWDSLWQELYCDWRKLWFNERIEPPSWLLGDMALAQGAKGVLFPSLANPSGMNLVLYTDNLAESDLLEAYDP
HGDLPRDARSWE

Download         Length: 519 bp

>T166547 NZ_CP074350:3190693-3190911 [Pantoea dispersa]
ATGAGCAACCCAGCCTTAACAAAAACAGACTATTTGATGCGACTGCGTCGTTGTCGCTCAATTGACACCCTTGAACGGGT
GATTGAAAAGAACAAGTATGAATTACCCGATGATGAGTTAGCGGTATTCTACTCCGCAGCCGATCACCGTCTGGCCGAGC
TGACCATGAACAAGCTCTATGACAAAGTGCCCGGATCTGTCTGGAAGTACGTCCGCTAA

Antitoxin


Download         Length: 143 a.a.        Molecular weight: 15798.88 Da        Isoelectric Point: 6.3333

>AT166547 WP_186255121.1 NZ_CP058321:982291-982719 [Halomonas sp. SH5A2]
MATAIEESHSEPMGYQAPDSFARFLADLKGVAREDRQPLINPKLFASALSMDIQTLASHAHVHRTTIYRAQGAEKLQRFL
REALRVLGAAADINGDFHDALFWFRNEPIGAFDYKTPEQLVSEGRADDLLRYVKALQAGVVG

Download         Length: 429 bp

>AT166547 NZ_CP074350:3190291-3190668 [Pantoea dispersa]
ATGGACGAATACTCACCGAAACGGCATGATATTGCCCAGCTTAAATTTCTGTGTGAGAACCTGTTTGACGAAAGTATGGC
GACGCTAACCGACAGCCATCACGGCTGGGTTAATGATCCCACTTCGCCAGGCAATTTACAGCTCAACGATTTGATTGAGC
ATATCGCCTCTTTCACGATGAATTACAAAATTAAGCATGTTGAAGATGAAGCGCTGATTACGCAAATCGATGAATATCTT
GATGATACCTTTATGCTGTTTAGCAGCTATGGAATCAATACCCAGGATCTTCAACGGTGGCAACGTTCAGCAAAACGCTT
ATTTAATCTGTTTGCCGAAGAGTGCGCTTATCTCCAGCAACCCAGCCATTCCTTTTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References