Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ(toxin)
Location 910401..911025 Replicon chromosome
Accession NZ_CP058285
Organism Helicobacter pylori strain BT302

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag HWU11_RS04295 Protein ID WP_237008078.1
Coordinates 910401..910667 (-) Length 89 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag HWU11_RS04300 Protein ID WP_237008940.1
Coordinates 910648..911025 (-) Length 126 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HWU11_RS04275 907044..907811 - 768 WP_042630550.1 ABC transporter ATP-binding protein -
HWU11_RS04280 907811..908791 - 981 WP_000921461.1 iron ABC transporter permease -
HWU11_RS04285 908784..909632 - 849 WP_237008077.1 SDR family oxidoreductase -
HWU11_RS04290 909772..910296 + 525 WP_128027642.1 acyl-CoA thioesterase -
HWU11_RS04295 910401..910667 - 267 WP_237008078.1 type II toxin-antitoxin system YafQ family toxin Toxin
HWU11_RS04300 910648..911025 - 378 WP_237008940.1 hypothetical protein Antitoxin
HWU11_RS04305 911351..913546 - 2196 WP_237008942.1 Hop family adhesin BabA -
HWU11_RS04320 914071..914714 + 644 Protein_848 helicase DnaB modulator -
HWU11_RS04325 914665..915777 - 1113 WP_237008079.1 hydrogenase formation protein HypD -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(3-88)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10152.15 Da        Isoelectric Point: 9.6560

>T166433 WP_237008078.1 NZ_CP058285:c910667-910401 [Helicobacter pylori]
VLKLNLKKSFQKDFDKLLLNGFDDSVLKEVILTLRKKEPLPPPFKDHALKGVWKPYRECHIKADVLLVCLVKGDELILLR
LGSHSELF

Download         Length: 267 bp

>T166433 NZ_CP074154:816662-817147 [Enterobacter asburiae]
GTGGGACGTGTAACAGCACCAGAACCGTTATCCAGTTCTCATCAACTTGCTGAGTTTGTCAGTGGTGAGGCTGTACTTGA
TGACTGGCTTAAACAGAGAGGATTAAAGAATCAGGCTCTCGGTGCCGCCCGAACGTTCGTTGTTTGTAAAACAGACACGA
AACAGGTTGCCGGTTTTTACTCTCTGGCCACGGGCAGTGTTAACCACGTGGAGGCAACGGGAAGCCTCAGGCGCAATATG
CCAGATCCCATCCCCGTAATCATTCTTGCTCGCCTGGCTGTCGATGTTTCATTCCGTGGAAAAGGGCTCGGGGCTGATTT
ACTGCATGATGCAGTTCTGCGCTGTTACCGTGTAGCTGAGAATATTGGAGTTCGTGCGATTATGGTTCATGCACTGACTG
AAGAAGCCAAAAGCTTTTACCTTCACCATGGCTTTAAGGCATCGCAAATCCAGGAGCGCACATTGTTTCTCAAATTACCA
CAGTAG

Antitoxin


Download         Length: 126 a.a.        Molecular weight: 14771.60 Da        Isoelectric Point: 7.1370

>AT166433 WP_237008940.1 NZ_CP058285:c911025-910648 [Helicobacter pylori]
MPNTTAKKDYTQYSEKQLFNLIHQLERKIKKMQNDRVSFKEKMAKELEKRDQNFKDKIDALNELLQKISQAFDDKRDCCF
GHETPNIQTQQAMREADNKETDLFVEDFSSYSNERKKALGVEAQS

Download         Length: 378 bp

>AT166433 NZ_CP074154:816408-816674 [Enterobacter asburiae]
ATGAAATCAGATGTTCAGCTCAACCTTAGAGCTAAGGAATCTCAAAGAGCACTCATTGATGCTGCAGCAGAGATTCTCCA
TAAATCACGCACAGACTTCATCCTGGAAATGGCATGTCAGGCTGCTGAGAATGTGATCCTCGATCGTCGCGTATTTAATT
TTAACGATGAGCAGTATGCAGAGTTTATCGATATGCTCGATGCACCAGTTACGGATGACGCTACCATTGGTAAACTCCTG
GGAAGGAAACCTCAGTGGGACGTGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References