Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/RHH(antitoxin)
Location 3408767..3409301 Replicon chromosome
Accession NZ_CP058278
Organism Flavobacterium sp. P2-65

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag HW120_RS15350 Protein ID WP_177735144.1
Coordinates 3409008..3409301 (+) Length 98 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag HW120_RS15345 Protein ID WP_177735142.1
Coordinates 3408767..3409015 (+) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HW120_RS15310 3403847..3404269 + 423 WP_177735128.1 hypothetical protein -
HW120_RS15315 3404572..3405351 - 780 WP_177735130.1 hypothetical protein -
HW120_RS15320 3405468..3406103 - 636 WP_177735132.1 hypothetical protein -
HW120_RS15325 3406172..3406717 - 546 WP_177735134.1 hypothetical protein -
HW120_RS15330 3406901..3407311 + 411 WP_177735136.1 hypothetical protein -
HW120_RS15335 3407453..3407923 + 471 WP_177735138.1 hypothetical protein -
HW120_RS15340 3407961..3408563 + 603 WP_177735140.1 hypothetical protein -
HW120_RS15345 3408767..3409015 + 249 WP_177735142.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
HW120_RS15350 3409008..3409301 + 294 WP_177735144.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
HW120_RS15355 3409371..3410297 + 927 WP_177735146.1 hypothetical protein -
HW120_RS15360 3410340..3411326 - 987 WP_177735148.1 amidase -
HW120_RS15365 3411537..3412061 - 525 WP_177735150.1 tail fiber protein -
HW120_RS15370 3412130..3413023 - 894 WP_177735152.1 tail fiber domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-93)

Antitoxin

Antitoxin ParD

(1-78)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 11393.93 Da        Isoelectric Point: 5.1099

>T166429 WP_177735144.1 NZ_CP058278:3409008-3409301 [Flavobacterium sp. P2-65]
MAKFYLTNKAVEDLGDIWNYTVEAWSENQAEIYYSLIIDSFQELASKPNQGKSYDVVERNVLGYKTGQHVIFYRIVTERE
IEVIRISHGMMDMKNHL

Download         Length: 294 bp

>T166429 NZ_CP074149:3730606-3730905 [Enterobacter sp. JBIWA008]
ATGATTAGTTATTTTCGGGATCAATGGCTTGAGGATTTTTTTCTTTACGGCAGATCGAGCAACGTTATTCCTTCAAATCT
GGAAACAGCGCTTGCGAGAAAGCTCGATATCATCAGGGCAGCAACCTCGCACAGGGATTTGCGATCGCCACCCGGCAATA
TGTATGAAGCATTGAATCCTCCGCTGAAGGGCTATTCCTCAATCCGGGTTAACAGGCAATACAGGCTCGTATTTCGCTGG
ACAGAGGGTAAAGCAGAAGATCTCTACCTCTCTCCACACAAGTACACGCAACACAAATGA

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9171.32 Da        Isoelectric Point: 10.0121

>AT166429 WP_177735142.1 NZ_CP058278:3408767-3409015 [Flavobacterium sp. P2-65]
MGRNTSISLGPHFESFIESTVSKGRFSNASEVVRAGLRLLEEEENRITVLRNAIQEGIESGRAENFDPKKHLETLKSKKK
NG

Download         Length: 249 bp

>AT166429 NZ_CP074149:3730916-3731263 [Enterobacter sp. JBIWA008]
ATGACACTTCAACAGGCACTCCGCAAACCCACCACGCCGGGCGACGTGTTGCAGTATGAGTATCTTGAACCGCTCAATCT
GAAAATCAGCGATCTGGCGGAGATGCTCAATGTTCACCGCAACACCATCAGCGCGCTGGTCAATAACAATCGCAAGCTTA
CTGCCGATATGGCGATCAAACTGGCAAAAGCCTTTGATACCACGATTGAATTTTGGCTGAACTTACAGCTGAACGTCGAT
ATCTGGGAAGCACAATCTAACTCCAGGACGCAGGAGGAGCTAAGCCGTATAAAGACCGTTGCGGACGTCATGGCTAAGCG
AAAATCTGGCCAGCCGGATGTAGCCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References