Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4537214..4537580 Replicon chromosome
Accession NZ_CP058243
Organism Xanthomonas campestris pv. raphani strain MAFF106181

Toxin (Protein)


Gene name EcnB Uniprot ID G0CKD4
Locus tag AD14011_RS19655 Protein ID WP_011270059.1
Coordinates 4537214..4537348 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID Q8P3Z2
Locus tag AD14011_RS19660 Protein ID WP_011038999.1
Coordinates 4537428..4537580 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AD14011_RS19635 4532478..4534130 - 1653 WP_162275546.1 M28 family peptidase -
AD14011_RS19640 4534295..4535239 - 945 WP_176994121.1 MBL fold metallo-hydrolase -
AD14011_RS19645 4535323..4536612 - 1290 WP_043922084.1 tryptophan--tRNA ligase -
AD14011_RS19650 4536772..4536981 - 210 WP_011038998.1 CsbD family protein -
AD14011_RS19655 4537214..4537348 - 135 WP_011270059.1 entericidin A/B family lipoprotein Toxin
AD14011_RS19660 4537428..4537580 - 153 WP_011038999.1 entericidin A/B family lipoprotein Antitoxin
AD14011_RS19665 4537691..4538614 - 924 WP_076057526.1 arginase -
AD14011_RS19670 4538928..4539389 + 462 WP_012439505.1 roadblock/LC7 domain-containing protein -
AD14011_RS19675 4539472..4539831 + 360 WP_011039002.1 hypothetical protein -
AD14011_RS19680 4539934..4540851 + 918 WP_076057143.1 hypothetical protein -
AD14011_RS19685 4540848..4541390 + 543 WP_042595653.1 GTPase -
AD14011_RS19690 4541725..4542408 + 684 WP_076057144.1 dTMP kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4431.27 Da        Isoelectric Point: 9.3487

>T166402 WP_011270059.1 NZ_CP058243:c4537348-4537214 [Xanthomonas campestris pv. raphani]
MKRAIALLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T166402 NZ_CP074147:566387-566662 [Serratia sp. JSRIV001]
ATGCGCATCGAATGGGACGACGTTGCGTTGCAAGATCGGGAACGCATTTTTGAATTTCTTTATCCACTCAATTCATTGGC
CGCGGAACAAGTTGATGATGAGATTGAACTTGCCGTTGAGTCTCTGCTAGAAAACCCAGAAATGGGCAGGCCTTGGTATG
GGGAAGCTCGCAAACTGGTGATCAGTAAAGCCTCCCTATTGCTGATTTATGTCATTTTGGATGAGGTGATAAAGGTTTTA
GCCGTCGCCCATCAGCGTGAAAAATTCCCCAATTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5173.15 Da        Isoelectric Point: 8.2782

>AT166402 WP_011038999.1 NZ_CP058243:c4537580-4537428 [Xanthomonas campestris pv. raphani]
MKRLLTLMVLGLFSAGMMTGCNTMAGAGKDMQGAGDKVEKTADKCSDGKC

Download         Length: 153 bp

>AT166402 NZ_CP074147:566091-566378 [Serratia sp. JSRIV001]
ATGGAAAGCCGTATCCAGTTTCGCATTGAAAATGAAACTAAACTGTTGGCACAGAAAGCTGCTGAAGCGAAAGGGACGAC
CTTAAGTGAAGCCTGTCGGCGTTTAGCGCAACAAATGGCGGACGATCAACGTGCTGCTGAAGAACACGAAAACTGGTTGA
AAGATAAGGTTGATGCAGCCTTTGCCCGTTTGCATGAAGGAGAGGCTGTTTATCTTACCCAGCGGCAAGCTGAGGAGAGA
ATGAGCGACTTTAAAGCCAAAGTCAGGGCGAAATACGCAACCAAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0H2XDQ0

Antitoxin

Source ID Structure
AlphaFold DB Q8P3Z2

References