Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2031512..2031657 Replicon chromosome
Accession NZ_CP058226
Organism Klebsiella pneumoniae strain KPCZA02

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2031548..2031650 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2031512..2031657 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HWQ20_RS09945 (HWQ20_09950) 2026642..2028702 + 2061 WP_004151449.1 oligopeptidase B -
HWQ20_RS09950 (HWQ20_09955) 2028706..2029365 - 660 WP_002911407.1 exodeoxyribonuclease X -
HWQ20_RS09955 (HWQ20_09960) 2029444..2029674 - 231 WP_002911406.1 DNA polymerase III subunit theta -
HWQ20_RS09960 (HWQ20_09965) 2029787..2030161 + 375 WP_004151448.1 CopC domain-containing protein YobA -
HWQ20_RS09965 (HWQ20_09970) 2030165..2031034 + 870 WP_062955019.1 copper homeostasis membrane protein CopD -
HWQ20_RS09970 (HWQ20_09975) 2031051..2031389 + 339 WP_002911404.1 YebY family protein -
- 2031512..2031657 - 146 - - Antitoxin
- 2031548..2031650 + 103 - - Toxin
HWQ20_RS09975 (HWQ20_09980) 2032025..2032168 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
HWQ20_RS09980 (HWQ20_09985) 2032273..2033241 - 969 WP_004151446.1 VirK/YbjX family protein -
HWQ20_RS09985 (HWQ20_09990) 2033398..2034051 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
HWQ20_RS09990 (HWQ20_09995) 2034048..2034239 - 192 WP_002911395.1 YebW family protein -
HWQ20_RS09995 (HWQ20_10000) 2034337..2034576 - 240 WP_002911393.1 YebV family protein -
HWQ20_RS10000 (HWQ20_10005) 2034692..2036125 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T166289 NZ_CP058226:2031548-2031650 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT166289 NZ_CP058226:c2031657-2031512 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References