Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2310792..2311060 Replicon chromosome
Accession NZ_CP058222
Organism Escherichia coli strain CFT073

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2310920..2311022 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2310792..2311060 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HW370_RS10920 2307344..2308006 - 663 WP_000944256.1 exodeoxyribonuclease X -
HW370_RS10925 2308030..2308686 - 657 WP_000011644.1 carbon-nitrogen hydrolase family protein YobB -
HW370_RS10930 2308789..2309019 - 231 WP_000916763.1 DNA polymerase III subunit theta -
HW370_RS10935 2309158..2309532 + 375 WP_000168747.1 CopC domain-containing protein YobA -
HW370_RS10940 2309536..2310408 + 873 WP_000879311.1 copper homeostasis membrane protein CopD -
HW370_RS10945 2310421..2310762 + 342 WP_000984819.1 YebY family protein -
- 2310792..2311060 - 269 - - Antitoxin
- 2310920..2311022 + 103 - - Toxin
HW370_RS10950 2311157..2311813 + 657 WP_000812743.1 protein-serine/threonine phosphatase -
HW370_RS10955 2311814..2312005 - 192 WP_001317886.1 YebW family protein -
HW370_RS10960 2312110..2312346 - 237 WP_001295499.1 YebV family protein -
HW370_RS10965 2312464..2313903 - 1440 WP_001704100.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T166235 NZ_CP058222:2310920-2311022 [Escherichia coli]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 269 bp

>AT166235 NZ_CP058222:c2311060-2310792 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References