Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2246798..2247066 Replicon chromosome
Accession NZ_CP058217
Organism Escherichia coli Nissle 1917

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2246926..2247028 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2246798..2247066 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HW372_RS10565 2243350..2244012 - 663 WP_000944256.1 exodeoxyribonuclease X -
HW372_RS10570 2244036..2244692 - 657 WP_000011644.1 carbon-nitrogen hydrolase family protein YobB -
HW372_RS10575 2244795..2245025 - 231 WP_000916763.1 DNA polymerase III subunit theta -
HW372_RS10580 2245164..2245538 + 375 WP_000168747.1 CopC domain-containing protein YobA -
HW372_RS10585 2245542..2246414 + 873 WP_000879311.1 copper homeostasis membrane protein CopD -
HW372_RS10590 2246427..2246768 + 342 WP_000984819.1 YebY family protein -
- 2246798..2247066 - 269 - - Antitoxin
- 2246926..2247028 + 103 - - Toxin
HW372_RS10595 2247163..2247819 + 657 WP_000812743.1 protein-serine/threonine phosphatase -
HW372_RS10600 2247820..2248011 - 192 WP_001317886.1 YebW family protein -
HW372_RS10605 2248116..2248352 - 237 WP_001295499.1 YebV family protein -
HW372_RS10610 2248470..2249909 - 1440 WP_001704100.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T166180 NZ_CP058217:2246926-2247028 [Escherichia coli Nissle 1917]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 269 bp

>AT166180 NZ_CP058217:c2247066-2246798 [Escherichia coli Nissle 1917]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References