Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ccdAB/CcdA(antitoxin)
Location 107..4377 Replicon plasmid pRHBSTW-00002_6
Accession NZ_CP058201
Organism Enterobacter roggenkampii strain RHBSTW-00002

Toxin (Protein)


Gene name ccdB Uniprot ID -
Locus tag HV027_RS23485 Protein ID WP_094309572.1
Coordinates 107..415 (+) Length 103 a.a.

Antitoxin (Protein)


Gene name ccdA Uniprot ID -
Locus tag HV027_RS23480 Protein ID WP_128312513.1
Coordinates 4377..107 (+) Length -1423 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HV027_RS23485 107..415 + 309 WP_094309572.1 CcdB family protein Toxin
HV027_RS23490 519..755 - 237 WP_037427059.1 MbeD family mobilization/exclusion protein -
HV027_RS23495 816..1301 - 486 WP_139592782.1 MbeB family mobilization protein -
HV027_RS23500 1288..2025 - 738 Protein_4 relaxase/mobilization nuclease domain-containing protein -
HV027_RS23505 1970..2305 - 336 WP_080202507.1 plasmid mobilization relaxosome protein MobC -
HV027_RS23510 2595..2990 + 396 WP_128312516.1 hypothetical protein -
HV027_RS23515 3033..3188 - 156 WP_181239571.1 hypothetical protein -
HV027_RS23520 3169..4095 - 927 WP_063448382.1 replication initiation protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..4509 4509


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin SymE-like

(20-71)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 103 a.a.        Molecular weight: 13219.95 Da        Isoelectric Point: 12.8085

>T166100 WP_094309572.1 NZ_CP058201:107-415 [Enterobacter roggenkampii]
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK
KKKKKKKKKKKKKKKKKKKKKKK

Download         Length: 309 bp

>T166100 NZ_CP074033:2456175-2456516 [Escherichia coli]
ATGACTGACATGCATTCTATTGCACAACCGTTCGAAGCAGAAGTCTCCCCGGCAAATAACCGTCAATTAACCGTGAGTTA
TGCGAGTCGCTACCCGGATTACAGCCGTATTCCCGCCATCACCCTGAAAGGTCAGTGGCTGGAAGCCGCCGGTTTTACCA
CCGGCACGGCGGTAGATGTCAAAGTGATGGAAGGCTGTATTGTCCTCACCGCCCAACCACTCGCCGTCGAAGAGAGCGAA
CTGATGCAGTCGCTGCGCCAGGTGTGCAAGCTGTCGGCACGTAAACAAAAGCAGGTGCAGGCGTTTATTGGAGTGATTGC
CGGTAAACAGAAAGTCGCGTAA

Antitoxin


Download         Length: -1423 a.a.        Molecular weight: Da        Isoelectric Point:

>AT166100 WP_128312513.1 NZ_CP058201:4377-107 [Enterobacter roggenkampii]

Download         Length: -4269 bp

>AT166100 NZ_CP074033:c2456180-2456104 [Escherichia coli]
AGTCATGATTACTATTCCTTAGAAATAGGGATTGTGATTAGCGGTGCGGGTGTGTTGGCGCACATCCGCACCGCGCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References