Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /RES-TIGR02293
Location 1569077..1569990 Replicon chromosome
Accession NZ_CP058160
Organism Enterobacter hormaechei strain RHBSTW-00083

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag HV059_RS07435 Protein ID WP_047052345.1
Coordinates 1569077..1569550 (-) Length 158 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag HV059_RS07440 Protein ID WP_047052347.1
Coordinates 1569547..1569990 (-) Length 148 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HV059_RS07415 1565236..1566546 + 1311 WP_181238460.1 type I-F CRISPR-associated protein Csy1 -
HV059_RS07420 1566543..1567478 + 936 WP_047052340.1 type I-F CRISPR-associated protein Csy2 -
HV059_RS07425 1567492..1568490 + 999 WP_047052342.1 type I-F CRISPR-associated protein Csy3 -
HV059_RS07430 1568500..1569054 + 555 WP_047052344.1 type I-F CRISPR-associated endoribonuclease Cas6/Csy4 -
HV059_RS07435 1569077..1569550 - 474 WP_047052345.1 RES domain-containing protein Toxin
HV059_RS07440 1569547..1569990 - 444 WP_047052347.1 DUF2384 domain-containing protein Antitoxin
HV059_RS07445 1571762..1571980 - 219 WP_002211347.1 translation initiation factor IF-1 -
HV059_RS07450 1572265..1572969 - 705 WP_047052381.1 leucyl/phenylalanyl-tRNA--protein transferase -
HV059_RS07455 1573015..1574736 - 1722 WP_003858307.1 cysteine/glutathione ABC transporter ATP-binding protein/permease CydC -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RES domain

(3-148)

Antitoxin

Antitoxin Xre/MbcA/ParS-like, toxin-binding domain

(94-144)


Sequences

Toxin        


Download         Length: 158 a.a.        Molecular weight: 17570.95 Da        Isoelectric Point: 5.1151

>T165965 WP_047052345.1 NZ_CP058160:c1569550-1569077 [Enterobacter hormaechei]
MIFYRLVTGRFASEAWSGSGANQYGGRWNHKGHPAVYVSTSISLASLEILVHVRKDTVLNQYQLFSINIPDDQIDYLDKA
WLPEDWQENPAPVSTMDLGTGWLQANSALALILPSCIIPYENNAILNPLHPAFRKALNSVELLPFDFDTRLAEKTAP

Download         Length: 474 bp

>T165965 NZ_CP074007:c2765415-2765239 [Escherichia coli]
GTGAAACAAAGCGAGTTCAGACGTTGGCTCGAATCTCAGGGCGTCGATGTAGCGAATGGCAGCAACCATTTGAAACTCAG
GTTTCATGGGAGGCGCAGTGTCATGCCGCGTCACCCCTGCGATGAGATTAAAGAACCATTGCGTAAAGCAATCCTGAAAC
AACTCGGTTTGAGTTAA

Antitoxin


Download         Length: 148 a.a.        Molecular weight: 16502.77 Da        Isoelectric Point: 6.4819

>AT165965 WP_047052347.1 NZ_CP058160:c1569990-1569547 [Enterobacter hormaechei]
MRTWVPAQRSADNTLWRYAGLPASRGMRLIEYLNQGLPVSVLDNIHEWTDMSKAEILRVTGINERNVARRKSTGRTLTPD
ESERVARFVRVLDAAVDYFGSKEEAWNWLQLPVRGLGNVAPVDLIATETGALEVTDLIGRLEHGVFA

Download         Length: 444 bp

>AT165965 NZ_CP074007:c2765193-2764777 [Escherichia coli]
ATGCGTTATCCCGTCACTCTTACACCCGCGCCGGAAGGCGGTTATATGGTTTCTTTTGTGGATATCCCTGAAGCGTTGAC
GCAGGGCGAAACTGTCGCTGAAGCGATGGAAGCGGCAAAAGATGCTTTACTGACCGCATTTGATTTTTATTTTGAAGATA
ACGAGCTTATCCCTTTACCTTCGCCATTAAATAGTCACGATCACTTTATTGAAGTACCTTTGAGCGTCGCCTCTAAGGTA
TTGCTGTTAAATGCTTTTTTACAGTCAGAAATCACTCAGCAAGAGTTAGCCAGGCGAATTGGCAAACCTAAACAGGAGAT
TACTCGCCTATTTAACTTGCATCATGCGACAAAAATCGACGCCGTCCAGCTCGCGGCAAAGGCGCTTGGCAAAGAGTTAT
CGCTGGTGATGGTTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References