Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2244527..2244695 Replicon chromosome
Accession NZ_CP058112
Organism Klebsiella grimontii strain RHBSTW-00181

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2244585..2244688 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2244527..2244695 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HV112_RS11000 2239653..2241713 + 2061 WP_064342867.1 oligopeptidase B -
HV112_RS11005 2241720..2242379 - 660 WP_004134816.1 exodeoxyribonuclease X -
HV112_RS11010 2242458..2242688 - 231 WP_004103351.1 DNA polymerase III subunit theta -
HV112_RS11015 2242824..2243198 + 375 WP_004134817.1 CopC domain-containing protein YobA -
HV112_RS11020 2243203..2244072 + 870 WP_004134819.1 copper homeostasis membrane protein CopD -
HV112_RS11025 2244089..2244427 + 339 WP_004103344.1 YebY family protein -
- 2244527..2244695 - 169 - - Antitoxin
- 2244585..2244688 + 104 - - Toxin
HV112_RS11030 2244813..2245772 - 960 WP_049085573.1 spore coat U domain-containing protein -
HV112_RS11035 2245787..2248117 - 2331 WP_049089570.1 fimbrial biogenesis outer membrane usher protein -
HV112_RS11040 2248120..2248884 - 765 WP_004134823.1 molecular chaperone -
HV112_RS11045 2248903..2249421 - 519 WP_049099811.1 spore coat U domain-containing protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2125542..2257377 131835


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T165820 NZ_CP058112:2244585-2244688 [Klebsiella grimontii]
GGCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 169 bp

>AT165820 NZ_CP058112:c2244695-2244527 [Klebsiella grimontii]
AATAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCCTTATAAGAATAGTTTACCGTGTCAGGTTTTCCAGTCCGTGACAAAAGTG
GACGAATAA

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References