Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1841947..1842092 Replicon chromosome
Accession NZ_CP057722
Organism Klebsiella pneumoniae strain RHB16-C24

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1841983..1842085 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1841947..1842092 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HVX23_RS08825 1837077..1839137 + 2061 WP_004151449.1 oligopeptidase B -
HVX23_RS08830 1839141..1839800 - 660 WP_002911407.1 exodeoxyribonuclease X -
HVX23_RS08835 1839879..1840109 - 231 WP_002911406.1 DNA polymerase III subunit theta -
HVX23_RS08840 1840222..1840596 + 375 WP_004151448.1 CopC domain-containing protein YobA -
HVX23_RS08845 1840600..1841469 + 870 WP_040224089.1 copper homeostasis membrane protein CopD -
HVX23_RS08850 1841486..1841824 + 339 WP_002911404.1 YebY family protein -
- 1841947..1842092 - 146 - - Antitoxin
- 1841983..1842085 + 103 - - Toxin
HVX23_RS08855 1842461..1842604 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
HVX23_RS08860 1842709..1843677 - 969 WP_181813154.1 VirK/YbjX family protein -
HVX23_RS08865 1843834..1844487 + 654 WP_181813155.1 protein-serine/threonine phosphatase -
HVX23_RS08870 1844484..1844675 - 192 WP_002911395.1 YebW family protein -
HVX23_RS08875 1844773..1845012 - 240 WP_002911393.1 YebV family protein -
HVX23_RS08880 1845128..1846561 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T165704 NZ_CP057722:1841983-1842085 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT165704 NZ_CP057722:c1842092-1841947 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References