Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | relBE/ParE-RelB |
| Location | 506124..506646 | Replicon | chromosome |
| Accession | NZ_CP057565 | ||
| Organism | Escherichia fergusonii strain RHB23-C01 | ||
Toxin (Protein)
| Gene name | relE | Uniprot ID | A0A7W3EN85 |
| Locus tag | HVX91_RS02325 | Protein ID | WP_046083069.1 |
| Coordinates | 506356..506646 (+) | Length | 97 a.a. |
Antitoxin (Protein)
| Gene name | relB | Uniprot ID | - |
| Locus tag | HVX91_RS02320 | Protein ID | WP_181812185.1 |
| Coordinates | 506124..506366 (+) | Length | 81 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| HVX91_RS02300 | 502042..503415 | + | 1374 | WP_181812184.1 | UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase | - |
| HVX91_RS02305 | 503498..504049 | - | 552 | WP_000166270.1 | ribosome-associated protein | - |
| HVX91_RS02310 | 504142..505494 | + | 1353 | WP_001162171.1 | metalloprotease PmbA | - |
| HVX91_RS02315 | 505547..505933 | + | 387 | WP_001232246.1 | cytochrome b562 | - |
| HVX91_RS02320 | 506124..506366 | + | 243 | WP_181812185.1 | type II toxin-antitoxin system RelB/DinJ family antitoxin | Antitoxin |
| HVX91_RS02325 | 506356..506646 | + | 291 | WP_046083069.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
| HVX91_RS02330 | 506647..507111 | - | 465 | WP_001106232.1 | anaerobic ribonucleoside-triphosphate reductase-activating protein | - |
| HVX91_RS02335 | 507269..509407 | - | 2139 | WP_000187805.1 | anaerobic ribonucleoside-triphosphate reductase | - |
| HVX91_RS02340 | 509801..511456 | - | 1656 | WP_181812186.1 | alpha,alpha-phosphotrehalase | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 97 a.a. Molecular weight: 11323.22 Da Isoelectric Point: 10.3007
>T165515 WP_046083069.1 NZ_CP057565:506356-506646 [Escherichia fergusonii]
MNYELAFDPRALKEWQKLGVTVREQFKKKLGDVLKRPRNPSAKLRDLPDCYKIKLRTLGYRRVYQVNDKELLVLVIAIGK
RENSAVYEDATKRLDE
MNYELAFDPRALKEWQKLGVTVREQFKKKLGDVLKRPRNPSAKLRDLPDCYKIKLRTLGYRRVYQVNDKELLVLVIAIGK
RENSAVYEDATKRLDE
Download Length: 291 bp
>T165515 NZ_CP073910:4269610-4269945 [Sphingobium phenoxybenzoativorans]
TTGGATATCGATTTTCGAAAGCGCAAGCTCGAGAAGACCTTCAATGCGCAAGCAGAATTGCTCAAAGCCTATGGGTTACC
CATGGCAAAGGCGATCATGAAGCGCATGACGGTGCTCCGGGCTGCGCGCACCCTGAGCCAAGTGCCGATTACGCCTCCCG
AACGAAGGCACCAGCTGACCGAGGACCGGGATGAGCAGTATGCAGTCGATTTGGTTCATCCCAAGCGACTGGTCTTTGAA
GTGAACCATGATCCAATCCCTCGCAGCGAAGACGGGGGAATCGATCTAACCAAGGTGACAGCGATAACGATCATCGAAGT
GGTCGATTATCACTGA
TTGGATATCGATTTTCGAAAGCGCAAGCTCGAGAAGACCTTCAATGCGCAAGCAGAATTGCTCAAAGCCTATGGGTTACC
CATGGCAAAGGCGATCATGAAGCGCATGACGGTGCTCCGGGCTGCGCGCACCCTGAGCCAAGTGCCGATTACGCCTCCCG
AACGAAGGCACCAGCTGACCGAGGACCGGGATGAGCAGTATGCAGTCGATTTGGTTCATCCCAAGCGACTGGTCTTTGAA
GTGAACCATGATCCAATCCCTCGCAGCGAAGACGGGGGAATCGATCTAACCAAGGTGACAGCGATAACGATCATCGAAGT
GGTCGATTATCACTGA
Antitoxin
Download Length: 81 a.a. Molecular weight: 9141.51 Da Isoelectric Point: 4.8409
>AT165515 WP_181812185.1 NZ_CP057565:506124-506366 [Escherichia fergusonii]
MATLNVRLDDKLKNEAYAVLEKLNITPTEAVRQLFQYVAENGRMPVKTLTVSDSEEALLRTVRERLANPEEAIKVRLDEL
MATLNVRLDDKLKNEAYAVLEKLNITPTEAVRQLFQYVAENGRMPVKTLTVSDSEEALLRTVRERLANPEEAIKVRLDEL
Download Length: 243 bp
>AT165515 NZ_CP073910:4269960-4271057 [Sphingobium phenoxybenzoativorans]
ATGGCGACCGCAGCCAATCAGTTCCGACCGGACTATGCCGTCCCACCCGGCTGGATCCTCGAAGAACGCCTGGAAGTTCA
TGGCATGTCGCAAGCCGAGTTTGCTCGGCGATGCGGTCGCTCGGCCAAGCTCATCAGCGAGATCATTGCCGGCAAGGCAC
CACTCGAGCCGGAAACTGCAATCCAGTTCGAGAAGGTTCTCGGAGTTGACGCCGATCTGTGGCTCTCGATCGAGTCCGGT
TATCAGCTCCATCGAGCGCGCGAGGCTGACGCAGCACGGGCAAAAGACGCCATCGCCTGGTCAAAGACATTCCCCATCAA
TGACCTGGTAAAGCGCCGCTGCTTCGCAAAACCCGTCAATCCCGTGGACGCGGTCTCAAAGCTGCTGGCGTTCTTCGGCG
TGGGTTCGCTCGACGCTTGGAATAGCCAGTACGGCTTGGCGAAGGTTGCCTATCGGCACTCGCCGTCGTTCAAAAGCAAT
GAGGTCGCGCTCGCGACCTGGCTCCGTCTCGGCGAACTCGATGCAGAGCAGCAGGAATGTGCAGATTATAGCGAAACGCA
GTTCAAGCTGGCGTTGAAGCAGATCCGTGCCTTGACGCGTGAACCCGTCGAGCAAGCCATTCCGCGCACGCGCGCACTGT
GCAATGAGGCTGGTGTGGCGCTTGCCTTGGTGCCGCCGCTTGCGAAAACCGCGCTTAGTGGTGCCGCATGGTGGATTTCG
CCTCGCAAGCCCGTGATCCAGCTCAGCGCACGCCACAAATCAGACGACCATTTGTGGTTCAGCTTCTTCCACGAAGCCGC
CCACATCCTCCTCCACAGCAAGAAGAGCGTTTTCGTCGATGATAAGTCGCGCGACGGGACCGATGAGGAAAAAGAGGCCG
ATGCGTGGGCCTGCAACACGCTCGTTTCGACGAGCGCGTGGAGGCAGTTTGTCGGGACGGGGCCGCGAAGCGAACGAGCG
GTGCTCGATTTCGCGGAGAGCCAGGGTATCGCGCCAGGCATCATTGTTGGCATGCTTCAGCATAGCGGGATCTTGCCGTG
GACTCATCTGAATGGATTGAAGACCCGCCTCAAATGGTCGACCGGCGCCGAGGACTGA
ATGGCGACCGCAGCCAATCAGTTCCGACCGGACTATGCCGTCCCACCCGGCTGGATCCTCGAAGAACGCCTGGAAGTTCA
TGGCATGTCGCAAGCCGAGTTTGCTCGGCGATGCGGTCGCTCGGCCAAGCTCATCAGCGAGATCATTGCCGGCAAGGCAC
CACTCGAGCCGGAAACTGCAATCCAGTTCGAGAAGGTTCTCGGAGTTGACGCCGATCTGTGGCTCTCGATCGAGTCCGGT
TATCAGCTCCATCGAGCGCGCGAGGCTGACGCAGCACGGGCAAAAGACGCCATCGCCTGGTCAAAGACATTCCCCATCAA
TGACCTGGTAAAGCGCCGCTGCTTCGCAAAACCCGTCAATCCCGTGGACGCGGTCTCAAAGCTGCTGGCGTTCTTCGGCG
TGGGTTCGCTCGACGCTTGGAATAGCCAGTACGGCTTGGCGAAGGTTGCCTATCGGCACTCGCCGTCGTTCAAAAGCAAT
GAGGTCGCGCTCGCGACCTGGCTCCGTCTCGGCGAACTCGATGCAGAGCAGCAGGAATGTGCAGATTATAGCGAAACGCA
GTTCAAGCTGGCGTTGAAGCAGATCCGTGCCTTGACGCGTGAACCCGTCGAGCAAGCCATTCCGCGCACGCGCGCACTGT
GCAATGAGGCTGGTGTGGCGCTTGCCTTGGTGCCGCCGCTTGCGAAAACCGCGCTTAGTGGTGCCGCATGGTGGATTTCG
CCTCGCAAGCCCGTGATCCAGCTCAGCGCACGCCACAAATCAGACGACCATTTGTGGTTCAGCTTCTTCCACGAAGCCGC
CCACATCCTCCTCCACAGCAAGAAGAGCGTTTTCGTCGATGATAAGTCGCGCGACGGGACCGATGAGGAAAAAGAGGCCG
ATGCGTGGGCCTGCAACACGCTCGTTTCGACGAGCGCGTGGAGGCAGTTTGTCGGGACGGGGCCGCGAAGCGAACGAGCG
GTGCTCGATTTCGCGGAGAGCCAGGGTATCGCGCCAGGCATCATTGTTGGCATGCTTCAGCATAGCGGGATCTTGCCGTG
GACTCATCTGAATGGATTGAAGACCCGCCTCAAATGGTCGACCGGCGCCGAGGACTGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|