Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 3831308..3831962 Replicon chromosome
Accession NZ_CP057506
Organism Citrobacter freundii strain RHB24-C05

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag HVY06_RS18055 Protein ID WP_096755799.1
Coordinates 3831308..3831715 (-) Length 136 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag HVY06_RS18060 Protein ID WP_096755798.1
Coordinates 3831696..3831962 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HVY06_RS18035 3827256..3828989 - 1734 WP_115257543.1 single-stranded-DNA-specific exonuclease RecJ -
HVY06_RS18040 3828995..3829708 - 714 WP_096755802.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
HVY06_RS18045 3829732..3830628 - 897 WP_096755801.1 site-specific tyrosine recombinase XerD -
HVY06_RS18050 3830741..3831262 + 522 WP_096755800.1 flavodoxin FldB -
HVY06_RS18055 3831308..3831715 - 408 WP_096755799.1 protein YgfX Toxin
HVY06_RS18060 3831696..3831962 - 267 WP_096755798.1 FAD assembly factor SdhE Antitoxin
HVY06_RS18065 3832219..3833199 + 981 WP_115257540.1 tRNA-modifying protein YgfZ -
HVY06_RS18070 3833279..3833938 - 660 WP_096755796.1 hemolysin III family protein -
HVY06_RS18075 3834102..3834413 - 312 WP_096755795.1 N(4)-acetylcytidine aminohydrolase -
HVY06_RS18080 3834466..3835194 + 729 WP_115259901.1 MurR/RpiR family transcriptional regulator -
HVY06_RS18085 3835315..3836748 + 1434 WP_181819688.1 6-phospho-beta-glucosidase BglA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-131)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 136 a.a.        Molecular weight: 15935.93 Da        Isoelectric Point: 11.2851

>T165463 WP_096755799.1 NZ_CP057506:c3831715-3831308 [Citrobacter freundii]
VVQWQSDLRVSWRAQWISLLIHGLVAVLILLMPWPLSYTPLWLILLSLVVFDCVRSQRRINACQGEIRLLMDGRLRWQGQ
EWSIVSAPWMIKTGMMLRLRSSTGKRQHLWLAADSMDDAEWRDLRRLILQPSMQK

Download         Length: 408 bp

>T165463 NZ_CP073890:c467579-467391 [Staphylococcus epidermidis]
ATGAGCTTACATTTCCAAATTTTGCTGTGGCTTTCTATCTTATTTATCATCGCAGGAACGATATTATTGGTAACAATGCT
TAAAACTAAAAAAGAAGAACGAAAAGAATCTTATCTAGGCTTTACTGTAATTTTCTTAATCTTTGGTTTTGCCATCTTAA
TTTATACTTTTATATTCGGAATTTTATAA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10570.10 Da        Isoelectric Point: 5.6311

>AT165463 WP_096755798.1 NZ_CP057506:c3831962-3831696 [Citrobacter freundii]
MDINNKARIHWACRRGMRELDISIMPFFEHEYDNLSDDEKRIFIRLLECDDPDLFNWLMNHGKPADAQLEQMVRLIQTRN
RERGPVAI

Download         Length: 267 bp

>AT165463 NZ_CP073890:c467861-467604 [Staphylococcus epidermidis]
ATGAAATTAAACAAAGCAAATATATTCAATTTGATATTCACCATTTTATTTTTTTCATTTAACATTCTCATAACCTATAA
CGCAAATATAGATTATAAGTTATGGTTAATACCTGGTTTAGCAATTTGTGGTTTTGCTCTTTTTTCAAGCTTGACCTTAG
TAATTATCTATAGTGATTTATTCAGTGAAATATTATTTTTTATCAACATTATCTTAGCACTGTATTACATTTATCCGATT
TTTTATGAATTTGTCTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References