165452

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) ykfI-yfjZ/CbtA-CbeA
Location 1209596..1210275 Replicon chromosome
Accession NZ_CP057506
Organism Citrobacter freundii strain RHB24-C05

Toxin (Protein)


Gene name ykfI Uniprot ID -
Locus tag HVY06_RS05760 Protein ID WP_181820051.1
Coordinates 1209596..1209937 (-) Length 114 a.a.

Antitoxin (Protein)


Gene name yfjZ Uniprot ID -
Locus tag HVY06_RS05765 Protein ID WP_181820052.1
Coordinates 1209958..1210275 (-) Length 106 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HVY06_RS05725 1204757..1205389 - 633 WP_117342165.1 fimbria biosynthesis transcriptional regulator FimZ -
HVY06_RS05730 1205980..1206702 - 723 WP_181820048.1 fimbriae Y protein -
HVY06_RS05735 1206725..1207450 - 726 WP_181820049.1 EAL domain-containing protein -
HVY06_RS05740 1207615..1208208 - 594 WP_115259165.1 fimbria biosynthesis transcriptional regulator FimW -
HVY06_RS05745 1208246..1208425 + 180 WP_115259164.1 hypothetical protein -
HVY06_RS05755 1208644..1209480 - 837 WP_181820050.1 DUF4942 domain-containing protein -
HVY06_RS05760 1209596..1209937 - 342 WP_181820051.1 TA system toxin CbtA family protein Toxin
HVY06_RS05765 1209958..1210275 - 318 WP_181820052.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
HVY06_RS05770 1210294..1210515 - 222 WP_181820053.1 DUF987 domain-containing protein -
HVY06_RS05775 1210524..1211000 - 477 WP_088583106.1 RadC family protein -
HVY06_RS05780 1211016..1211474 - 459 WP_181820054.1 antirestriction protein -
HVY06_RS05785 1211571..1211810 - 240 WP_181820055.1 DUF905 domain-containing protein -
HVY06_RS05790 1211965..1212438 - 474 WP_181820056.1 hypothetical protein -
HVY06_RS05795 1212460..1212942 - 483 Protein_1133 GntR family transcriptional regulator -
HVY06_RS05800 1213159..1213980 - 822 WP_181820057.1 DUF945 domain-containing protein -
HVY06_RS05805 1214071..1214934 - 864 WP_181820326.1 GTPase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(2-112)

Antitoxin

Antitoxin CbeA

(5-104)


Sequences

Toxin        


Download         Length: 114 a.a.        Molecular weight: 13001.98 Da        Isoelectric Point: 10.4208

>T165452 WP_181820051.1 NZ_CP057506:c1209937-1209596 [Citrobacter freundii]
MKPQSAATSRAVKPCLTPVAVWQMLLTRLLEQHYGLTLNDTPFIDETVIQNHINAGITLADAVNFLVDKYELVRIDRRRF
SWQEQSPYLRAVDILRARQATGLLRQNRNNAVR

Download         Length: 342 bp

>T165452 NZ_CP073881:1024828-1025007 [Staphylococcus epidermidis]
ATGGCGAACAAAAAAGATTCCAAATTAAATTATCATGAAGAAGAAAATGCTATGGTTACCGACTTAGATGATTTAAAAGA
ATTAGGAAAAGAAATGGAACAGATTTCACAGGAAAATGATGAAGAAAAATTAAATCAATCTCATGATAACGAAGTTCGTT
CAGATTTAAAAAAACAGTAA

Antitoxin


Download         Length: 106 a.a.        Molecular weight: 11984.61 Da        Isoelectric Point: 7.3232

>AT165452 WP_181820052.1 NZ_CP057506:c1210275-1209958 [Citrobacter freundii]
MSNITWGLQRDITPRLGARLVQERNRLHYLADRASITGKFSDAECQKLDETFPHFISQMESMLTTGEMNPRHAHCVTLYH
NGFTCEADTLGSCGYVYIAVYPTKR

Download         Length: 318 bp

>AT165452 NZ_CP073881:1024205-1024804 [Staphylococcus epidermidis]
ATGGCAATGAATTTTAAAGTATTTGATAATAGTGAAAAAGTAGCAGAATATACTGCAGATATTCTACGTAAGCAGTTTAA
TAATAATCCAACTACTATTGCAGGATTTCATTTGAGCAAAGAACATGCACCAGTGTTTGATGAACTTAAGAAAAATGTAG
AAAATCATACAGTTGATTTCAGTCAAATAAATATTTTAGATTATGATGATAATCATTCTTATTATGAGGCTTTGGGTGTG
CCAACAGGCCAAATTTATTCCATTTCTTACGAAAATGATGCAATTGACTTTATCTCAGATAAGATTAAGACTAAAGAAAA
TAAAGGCAAACTGACAATGCAAGTCCTTACGATTGATGAAAATGGTAAACTTGACATTAGCGTTCGTCAAGGTTTGATGG
AAGCTAGAGAAATTTTCTTAGTTATTACTGGTGCTAATAAACGCGATATGGTAGAAAAACTTTACCGTGAAAATGGTAAG
ACTAGTTTTGAACCATCGGATTTAAAAGCACACCGTATGGTCAATGTTATCTTAGATAAAGAAGCGGCTGCAGGCTTACC
TGAAGACGTAAAAGAGTACTTCACTGCACGTTTTGCATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References