165403

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 3951078..3951613 Replicon chromosome
Accession NZ_CP057483
Organism Citrobacter sp. RHB25-C09

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag HVY19_RS18715 Protein ID WP_181682098.1
Coordinates 3951326..3951613 (+) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag HVY19_RS18710 Protein ID WP_181682097.1
Coordinates 3951078..3951329 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HVY19_RS18685 3946859..3947617 + 759 WP_181682093.1 phosphonate C-P lyase system protein PhnK -
HVY19_RS18690 3947727..3948407 + 681 WP_181682094.1 phosphonate C-P lyase system protein PhnL -
HVY19_RS18695 3948404..3949540 + 1137 WP_181682095.1 alpha-D-ribose 1-methylphosphonate 5-triphosphate diphosphatase -
HVY19_RS18700 3949543..3950088 + 546 WP_181682096.1 ribose 1,5-bisphosphokinase -
HVY19_RS18705 3950213..3950971 + 759 WP_181684330.1 phosphonate metabolism protein PhnP -
HVY19_RS18710 3951078..3951329 + 252 WP_181682097.1 antitoxin Antitoxin
HVY19_RS18715 3951326..3951613 + 288 WP_181682098.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
HVY19_RS18720 3951610..3951939 - 330 WP_181682099.1 hypothetical protein -
HVY19_RS18725 3952018..3952641 - 624 WP_181684331.1 GNAT family N-acetyltransferase -
HVY19_RS18730 3952817..3955072 - 2256 WP_181682100.1 response regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-83)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11119.15 Da        Isoelectric Point: 10.5089

>T165403 WP_181682098.1 NZ_CP057483:3951326-3951613 [Citrobacter sp. RHB25-C09]
MSYTVKFREDALKEWRKLDTPIQQQFAKKLKKCCDNPHISSARLRGMKDCYKIKLKTSGFRLVYQVIDGMLVIAVVAVGK
RERSEVYHLASERLR

Download         Length: 288 bp

>T165403 NZ_CP073857:c1688531-1688352 [Staphylococcus epidermidis]
ATGGCGAACAAAAAAGATTCCAAATTAAATTATCATGAAGAAGAAAATGCTATGGTTACCGACTTAGATGATTTAAAAGA
ATTAGGAAAAGAAATGGAACAGATTTCACAGGAAAATGATGAAGAAAAATTAAATCAATCTCATGATAACGAAGTTCGTT
CAGATTTAAAAAAACAGTAA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9249.55 Da        Isoelectric Point: 4.1469

>AT165403 WP_181682097.1 NZ_CP057483:3951078-3951329 [Citrobacter sp. RHB25-C09]
MPHIILSDTTASVSELKKNPMATVNAGDGYPVAILNRNQPAFYCVPAELYEKMLDALDDQQLVKLVQERSQQPLVDVDLD
SYL

Download         Length: 252 bp

>AT165403 NZ_CP073857:c1689154-1688555 [Staphylococcus epidermidis]
ATGGCAATGAATTTTAAAGTATTTGATAATAGTGAAAAAGTAGCAGAATATACTGCAGATATTCTACGTAAGCAGTTTAA
TAATAATCCAACTACTATTGCAGGATTTCATTTGAGCAAAGAACATGCACCAGTGTTTGATGAACTTAAGAAAAATGTAG
AAAATCATACAGTTGATTTCAGTCAAATAAATATTTTAGATTATGATGATAATCATTCTTATTATGAGGCTTTGGGTGTG
CCAACAGGCCAAATTTATTCCATTTCTTACGAAAATGATGCAATTGACTTTATCTCAGATAAGATTAAGACTAAAGAAAA
TAAAGGCAAACTGACAATGCAAGTCCTTACGATTGATGAAAATGGTAAACTTGACATTAGCGTTCGTCAAGGTTTGATGG
AAGCTAGAGAAATTTTCTTAGTTATTACTGGTGCTAATAAACGCGATATGGTAGAAAAACTTTACCGTGAAAATGGTAAG
ACTAGTTTTGAACCATCGGATTTAAAAGCACACCGTATGGTCAATGTTATCTTAGATAAAGAAGCGGCTGCAGGCTTACC
TGAAGACGTAAAAGAGTACTTCACTGCACGTTTTGCATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References