Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 3646623..3647277 Replicon chromosome
Accession NZ_CP057483
Organism Citrobacter sp. RHB25-C09

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag HVY19_RS17200 Protein ID WP_181681689.1
Coordinates 3646623..3647030 (-) Length 136 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag HVY19_RS17205 Protein ID WP_181681690.1
Coordinates 3647011..3647277 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HVY19_RS17180 3642579..3644312 - 1734 WP_181681685.1 single-stranded-DNA-specific exonuclease RecJ -
HVY19_RS17185 3644318..3645031 - 714 WP_181681686.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
HVY19_RS17190 3645055..3645951 - 897 WP_181681687.1 site-specific tyrosine recombinase XerD -
HVY19_RS17195 3646052..3646573 + 522 WP_181681688.1 flavodoxin FldB -
HVY19_RS17200 3646623..3647030 - 408 WP_181681689.1 protein YgfX Toxin
HVY19_RS17205 3647011..3647277 - 267 WP_181681690.1 FAD assembly factor SdhE Antitoxin
HVY19_RS17210 3647534..3648514 + 981 WP_181681691.1 tRNA-modifying protein YgfZ -
HVY19_RS17215 3648667..3649326 - 660 WP_181681692.1 hemolysin III family protein -
HVY19_RS17220 3649486..3649797 - 312 WP_181681693.1 N(4)-acetylcytidine aminohydrolase -
HVY19_RS17225 3649895..3651328 + 1434 WP_181681694.1 6-phospho-beta-glucosidase BglA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-131)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 136 a.a.        Molecular weight: 15747.70 Da        Isoelectric Point: 10.5767

>T165401 WP_181681689.1 NZ_CP057483:c3647030-3646623 [Citrobacter sp. RHB25-C09]
VVLWQSDLRVSWRAQWLSLLLHGLVAAVILLMPWPLSYTPLWLILLSLVVFDCVRSQRRINACQGEVKLLMDGRLRWHGR
DWSIVSAPWIIKSGMMLRLRSDTGKRQHLWLAADSMDQTEWRDLCRLMLQPSTLG

Download         Length: 408 bp

>T165401 NZ_CP073855:c2031356-2031147 [Staphylococcus epidermidis]
ATGAAATTGAAAAAAGGATTGATAAATGTTTCAGGTATTAAAACAACTGAACAAGCTAAACAGCTCAAAGATCATTTATC
TAAGATGATAGGCATCAATAGTGTGGATATCGATTACCAAATGAATGAGATTCGAGTAGAATTTGACACTCCTGCAAATT
TAAATAACATTGAAAAAGAAATTTACGATTACGGATTTCGTATTTTGTAA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10516.05 Da        Isoelectric Point: 5.1496

>AT165401 WP_181681690.1 NZ_CP057483:c3647277-3647011 [Citrobacter sp. RHB25-C09]
MDINNKARIHWACRRGMRELDISIMPFFEHEYDTLSDDEKRIFIRLLECDDPDLFNWLMNHGKPADAELEQMVKLIQTRN
RDRGPVAI

Download         Length: 267 bp

>AT165401 NZ_CP073855:c2031656-2031363 [Staphylococcus epidermidis]
ATGGCAGACATGGAGAGTGCACATCACTCAGAGCAAATAAAAACAAATTTAAAATCAAGATTAAATAGAATAGAAGGTCA
AGTAAGAGCAATAAATCGTATGATTGATGATGACGTTTACTGTGATGATGTACTAACTCAAATTAGAGCAACACGTTCAG
CATTGAATAGTGTAGCTACTAAATTACTAGACCATCACATGAAAGGTTGTATTATGGAAAAAATAAACGACGGTGCGCAA
GAAGAAGCAATGGATGAATTGCTCGTGACATTCCAAAAATTAATAAAAGATTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References