Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1980190..1980335 Replicon chromosome
Accession NZ_CP057459
Organism Klebsiella pneumoniae strain RHB26-C08

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1980226..1980328 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1980190..1980335 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HVY29_RS09495 1975320..1977380 + 2061 WP_032419805.1 oligopeptidase B -
HVY29_RS09500 1977384..1978043 - 660 WP_002911407.1 exodeoxyribonuclease X -
HVY29_RS09505 1978122..1978352 - 231 WP_002911406.1 DNA polymerase III subunit theta -
HVY29_RS09510 1978465..1978839 + 375 WP_020316569.1 CopC domain-containing protein YobA -
HVY29_RS09515 1978843..1979712 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
HVY29_RS09520 1979729..1980067 + 339 WP_002911404.1 YebY family protein -
- 1980190..1980335 - 146 - - Antitoxin
- 1980226..1980328 + 103 - - Toxin
HVY29_RS09525 1980703..1980846 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
HVY29_RS09530 1980951..1981919 - 969 WP_014907334.1 VirK/YbjX family protein -
HVY29_RS09535 1982076..1982729 + 654 WP_009484457.1 protein-serine/threonine phosphatase -
HVY29_RS09540 1982726..1982917 - 192 WP_002911395.1 YebW family protein -
HVY29_RS09545 1983015..1983254 - 240 WP_002911393.1 YebV family protein -
HVY29_RS09550 1983370..1984803 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T165314 NZ_CP057459:1980226-1980328 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT165314 NZ_CP057459:c1980335-1980190 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References