Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1908862..1909007 Replicon chromosome
Accession NZ_CP057099
Organism Klebsiella pneumoniae strain RHB38-C06

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1908898..1909000 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1908862..1909007 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HVZ68_RS09450 1903992..1906052 + 2061 WP_004151449.1 oligopeptidase B -
HVZ68_RS09455 1906056..1906715 - 660 WP_021440386.1 exodeoxyribonuclease X -
HVZ68_RS09460 1906794..1907024 - 231 WP_002911406.1 DNA polymerase III subunit theta -
HVZ68_RS09465 1907137..1907511 + 375 WP_004151448.1 CopC domain-containing protein YobA -
HVZ68_RS09470 1907515..1908384 + 870 WP_023282759.1 copper homeostasis membrane protein CopD -
HVZ68_RS09475 1908401..1908739 + 339 WP_002911404.1 YebY family protein -
- 1908862..1909007 - 146 - - Antitoxin
- 1908898..1909000 + 103 - - Toxin
HVZ68_RS09480 1909375..1909518 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
HVZ68_RS09485 1909623..1910591 - 969 WP_004151446.1 VirK/YbjX family protein -
HVZ68_RS09490 1910748..1911401 + 654 WP_004175436.1 protein-serine/threonine phosphatase -
HVZ68_RS09495 1911398..1911589 - 192 WP_002911395.1 YebW family protein -
HVZ68_RS09500 1911687..1911926 - 240 WP_002911393.1 YebV family protein -
HVZ68_RS09505 1912042..1913475 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T164750 NZ_CP057099:1908898-1909000 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT164750 NZ_CP057099:c1909007-1908862 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References