Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | PanAT/DUF4065(antitoxin) |
Location | 338085..339073 | Replicon | chromosome |
Accession | NZ_CP057093 | ||
Organism | Escherichia fergusonii strain RHB38-C07 |
Toxin (Protein)
Gene name | panT | Uniprot ID | - |
Locus tag | HVZ69_RS01595 | Protein ID | WP_014640052.1 |
Coordinates | 338687..339073 (+) | Length | 129 a.a. |
Antitoxin (Protein)
Gene name | panA | Uniprot ID | A0A0J5Z6D5 |
Locus tag | HVZ69_RS01590 | Protein ID | WP_000458584.1 |
Coordinates | 338085..338657 (+) | Length | 191 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
HVZ69_RS01565 | 334213..334581 | + | 369 | WP_181588230.1 | diacylglycerol kinase | - |
HVZ69_RS01570 | 334691..335299 | + | 609 | WP_000646099.1 | transcriptional repressor LexA | - |
HVZ69_RS01575 | 335372..336697 | + | 1326 | WP_181598218.1 | MATE family efflux transporter DinF | - |
HVZ69_RS01580 | 336829..337038 | + | 210 | WP_001030605.1 | CsbD family protein | - |
HVZ69_RS01585 | 337089..337604 | - | 516 | WP_181588232.1 | zinc uptake transcriptional repressor Zur | - |
HVZ69_RS01590 | 338085..338657 | + | 573 | WP_000458584.1 | SocA family protein | Antitoxin |
HVZ69_RS01595 | 338687..339073 | + | 387 | WP_014640052.1 | hypothetical protein | Toxin |
HVZ69_RS01600 | 339113..339286 | + | 174 | WP_000390072.1 | hypothetical protein | - |
HVZ69_RS01605 | 339334..339615 | - | 282 | WP_001093917.1 | pyocin activator PrtN family protein | - |
HVZ69_RS01610 | 339652..340224 | - | 573 | WP_001061348.1 | 3'-5' exoribonuclease | - |
HVZ69_RS01615 | 340224..341033 | - | 810 | WP_000206745.1 | hypothetical protein | - |
HVZ69_RS01620 | 341033..341395 | - | 363 | WP_001242749.1 | phage protein | - |
HVZ69_RS01625 | 341386..341922 | - | 537 | WP_062858077.1 | 5'-deoxynucleotidase | - |
HVZ69_RS01630 | 342050..342874 | - | 825 | WP_001569327.1 | DUF2303 family protein | - |
HVZ69_RS01635 | 342940..343302 | - | 363 | WP_000135680.1 | hypothetical protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 129 a.a. Molecular weight: 14465.40 Da Isoelectric Point: 5.4833
>T164716 WP_014640052.1 NZ_CP057093:338687-339073 [Escherichia fergusonii]
VLAPTGPCNHLHVICNDPVYYPVNDCYCVLVVNISSIKDGVPHDPSCVLNSGDHRFIKHPSYVVYAEAIIWRVDNMVRKQ
RSGEISVHDDMPEATFNRILDGFDISDEVTPKNLKFKNKYCVSSIDDE
VLAPTGPCNHLHVICNDPVYYPVNDCYCVLVVNISSIKDGVPHDPSCVLNSGDHRFIKHPSYVVYAEAIIWRVDNMVRKQ
RSGEISVHDDMPEATFNRILDGFDISDEVTPKNLKFKNKYCVSSIDDE
Download Length: 387 bp
>T164716 NZ_CP073110:c2959240-2958374 [Agrobacterium rhizogenes]
ATGGCTAAAGAGATCAAGAACATCGGCGCCTCGGTGCGCGCACGTCTGCTGCAACTCGCCAAGGCAAGTGGCCAGAGCTT
CGACCTGGTTCTGACCCGCTTCGCCCTCGAGCGGCTGCTCTTCCGGCTCAGCCGGTCAAGCCATGCCGACCGTTTCGTGC
TGAAGGGCGCCATGTTGATGATGAGTTGGTTCGACGACCCACACCGCGGCACGCGCGACCTTGATCTGCTGGGTTTCGGT
GATCCGAGTGCGGAGCTAATGCTGGCGACGTTTCGGGAGATCCTGGCGCAGGACGCCAGCGATGGCGTCGAGTTCGACGC
TGACGCACTTCGCGTCGACCGCATTCGCGAAGAGCTGGAATATGGCGGGCTGAGGCTGAGGACGACAGCTTCGATCAGCG
GCGCCCGGATCAGCCTGACGATCGACATCGGCTTTGGCGATGCGCTGGAGCCTGGCACCGAGGAGCTGGACTATCCTTCG
ATGCTGGACTTTCCCATGCCCCGGCTGCGGGGCTACGCCCGGGAGACTGTCATTGCCGAGAAATTCCAGGCGATGGTGGC
GCTGGGGCGTGCCAACACTCGGATGAAAGATTTCTACGACATCTGGATTCTCAGCAGGTCGTTCGATTTCAGCAATGACA
GGTTGGTGCGGGCAATTACCGGCACTTTCGAACGGCGTGAGACGCCGATCCCAACGGTGCTACCGGATGCTTTAACGGAA
GCATTTGCCCAGGATCAGCAAAAGCAACGGCAATGGCGAGCGTTTGTTGAAGACGTTGCCCATAACCCGGGTGAATTGAT
GGATGTCATCACGGATATCGCCGGATTCCTGATGCCTCATGCCGCAGCCGCGAGCCGGGGCAAATGA
ATGGCTAAAGAGATCAAGAACATCGGCGCCTCGGTGCGCGCACGTCTGCTGCAACTCGCCAAGGCAAGTGGCCAGAGCTT
CGACCTGGTTCTGACCCGCTTCGCCCTCGAGCGGCTGCTCTTCCGGCTCAGCCGGTCAAGCCATGCCGACCGTTTCGTGC
TGAAGGGCGCCATGTTGATGATGAGTTGGTTCGACGACCCACACCGCGGCACGCGCGACCTTGATCTGCTGGGTTTCGGT
GATCCGAGTGCGGAGCTAATGCTGGCGACGTTTCGGGAGATCCTGGCGCAGGACGCCAGCGATGGCGTCGAGTTCGACGC
TGACGCACTTCGCGTCGACCGCATTCGCGAAGAGCTGGAATATGGCGGGCTGAGGCTGAGGACGACAGCTTCGATCAGCG
GCGCCCGGATCAGCCTGACGATCGACATCGGCTTTGGCGATGCGCTGGAGCCTGGCACCGAGGAGCTGGACTATCCTTCG
ATGCTGGACTTTCCCATGCCCCGGCTGCGGGGCTACGCCCGGGAGACTGTCATTGCCGAGAAATTCCAGGCGATGGTGGC
GCTGGGGCGTGCCAACACTCGGATGAAAGATTTCTACGACATCTGGATTCTCAGCAGGTCGTTCGATTTCAGCAATGACA
GGTTGGTGCGGGCAATTACCGGCACTTTCGAACGGCGTGAGACGCCGATCCCAACGGTGCTACCGGATGCTTTAACGGAA
GCATTTGCCCAGGATCAGCAAAAGCAACGGCAATGGCGAGCGTTTGTTGAAGACGTTGCCCATAACCCGGGTGAATTGAT
GGATGTCATCACGGATATCGCCGGATTCCTGATGCCTCATGCCGCAGCCGCGAGCCGGGGCAAATGA
Antitoxin
Download Length: 191 a.a. Molecular weight: 21973.21 Da Isoelectric Point: 6.0283
>AT164716 WP_000458584.1 NZ_CP057093:338085-338657 [Escherichia fergusonii]
MFCEEKVAQMAAYLLLKRGGRMAYLKLMKLLYLSNRQSILKHGRMIGEDSLYSMKFGPVMSNTLNLIRGKAEGIGDYWYN
LIETNGHNVSLRSDPREMDADEVFDELSRADIRILDEIYSRYGHMNRFDLANMTHLESVCPEWHDPGNSRKPIDLKEMLI
SEGKSEDEANRIIGKMEESQKLKEFSLQLS
MFCEEKVAQMAAYLLLKRGGRMAYLKLMKLLYLSNRQSILKHGRMIGEDSLYSMKFGPVMSNTLNLIRGKAEGIGDYWYN
LIETNGHNVSLRSDPREMDADEVFDELSRADIRILDEIYSRYGHMNRFDLANMTHLESVCPEWHDPGNSRKPIDLKEMLI
SEGKSEDEANRIIGKMEESQKLKEFSLQLS
Download Length: 573 bp
>AT164716 NZ_CP073110:c2959850-2959233 [Agrobacterium rhizogenes]
ATGCCCGAATCTATCTCCCAGCGCCAAATCGCCCACGCCCTCCTGACGGCGCGTGGGATCGCGCGTCTTGTAGAGCTGCG
CGATGCTGGCGTAACGGCCGCAACGATGAGCCGCATGGAGCGGGATGGGGAGGTGCTCCGGCTTGCACGGGGCCTTTATC
AGCTCTCCGACGCGCCGCTCGACGCCAACCACAGTCTGGCCGAGGCCGCTAAACGCCTACCCAAGGGTGTTGTCTGCCTT
GTGTCGGCCCTCGCGTTCCACGGCCTGACCGACCAGCTTCCGAAGCAGGTGTGGCTGGCGATAGGGCGGAAGGATTGGGC
TCCCAAACCCGACAGTACGCCTATTCGGATCGTGCGCTTCACCGACAGACTGCTCAATGAAAGCGTAGAGACCCATGTCG
TCGAAGGTGTGCCCGTAAAGGTCTTTGGGATCGTCAAAACAATCGCGGACTGTTTCCGATATCGCAACAAGATCGGTCTG
TCGGTGGCGATCGAGGGCCTCCAAGAAGTGCTCCGTCAGCGTAAGGCCACCCCCGGTGAAATTGCCAGGCAGGCCGAGCG
TGGCGGTGTCGCCACGGTCATCCGGCCGTATATCGAGGCGCTGACTGCCAATGGCTAA
ATGCCCGAATCTATCTCCCAGCGCCAAATCGCCCACGCCCTCCTGACGGCGCGTGGGATCGCGCGTCTTGTAGAGCTGCG
CGATGCTGGCGTAACGGCCGCAACGATGAGCCGCATGGAGCGGGATGGGGAGGTGCTCCGGCTTGCACGGGGCCTTTATC
AGCTCTCCGACGCGCCGCTCGACGCCAACCACAGTCTGGCCGAGGCCGCTAAACGCCTACCCAAGGGTGTTGTCTGCCTT
GTGTCGGCCCTCGCGTTCCACGGCCTGACCGACCAGCTTCCGAAGCAGGTGTGGCTGGCGATAGGGCGGAAGGATTGGGC
TCCCAAACCCGACAGTACGCCTATTCGGATCGTGCGCTTCACCGACAGACTGCTCAATGAAAGCGTAGAGACCCATGTCG
TCGAAGGTGTGCCCGTAAAGGTCTTTGGGATCGTCAAAACAATCGCGGACTGTTTCCGATATCGCAACAAGATCGGTCTG
TCGGTGGCGATCGAGGGCCTCCAAGAAGTGCTCCGTCAGCGTAAGGCCACCCCCGGTGAAATTGCCAGGCAGGCCGAGCG
TGGCGGTGTCGCCACGGTCATCCGGCCGTATATCGAGGCGCTGACTGCCAATGGCTAA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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