Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1973382..1973527 Replicon chromosome
Accession NZ_CP057069
Organism Klebsiella pneumoniae strain RHB39-C09

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1973418..1973520 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1973382..1973527 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HVZ81_RS09645 1968512..1970572 + 2061 WP_004151449.1 oligopeptidase B -
HVZ81_RS09650 1970576..1971235 - 660 WP_002911407.1 exodeoxyribonuclease X -
HVZ81_RS09655 1971314..1971544 - 231 WP_002911406.1 DNA polymerase III subunit theta -
HVZ81_RS09660 1971657..1972031 + 375 WP_004151448.1 CopC domain-containing protein YobA -
HVZ81_RS09665 1972035..1972904 + 870 WP_004175431.1 copper homeostasis membrane protein CopD -
HVZ81_RS09670 1972921..1973259 + 339 WP_002911404.1 YebY family protein -
- 1973382..1973527 - 146 - - Antitoxin
- 1973418..1973520 + 103 - - Toxin
HVZ81_RS09675 1973895..1974038 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
HVZ81_RS09680 1974143..1975111 - 969 WP_014907334.1 VirK/YbjX family protein -
HVZ81_RS09685 1975268..1975921 + 654 WP_020804905.1 protein-serine/threonine phosphatase -
HVZ81_RS09690 1975918..1976109 - 192 WP_002911395.1 YebW family protein -
HVZ81_RS09695 1976207..1976446 - 240 WP_002911393.1 YebV family protein -
HVZ81_RS09700 1976562..1977995 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T164703 NZ_CP057069:1973418-1973520 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT164703 NZ_CP057069:c1973527-1973382 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References