Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1848754..1848899 Replicon chromosome
Accession NZ_CP057034
Organism Klebsiella pneumoniae strain RHB39-C24

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1848790..1848892 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1848754..1848899 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HVZ90_RS09030 1843884..1845944 + 2061 WP_004151449.1 oligopeptidase B -
HVZ90_RS09035 1845948..1846607 - 660 WP_021440386.1 exodeoxyribonuclease X -
HVZ90_RS09040 1846686..1846916 - 231 WP_002911406.1 DNA polymerase III subunit theta -
HVZ90_RS09045 1847029..1847403 + 375 WP_004151448.1 CopC domain-containing protein YobA -
HVZ90_RS09050 1847407..1848276 + 870 WP_023282759.1 copper homeostasis membrane protein CopD -
HVZ90_RS09055 1848293..1848631 + 339 WP_002911404.1 YebY family protein -
- 1848754..1848899 - 146 - - Antitoxin
- 1848790..1848892 + 103 - - Toxin
HVZ90_RS09060 1849267..1849410 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
HVZ90_RS09065 1849515..1850483 - 969 WP_004151446.1 VirK/YbjX family protein -
HVZ90_RS09070 1850640..1851293 + 654 WP_004175436.1 protein-serine/threonine phosphatase -
HVZ90_RS09075 1851290..1851481 - 192 WP_002911395.1 YebW family protein -
HVZ90_RS09080 1851579..1851818 - 240 WP_002911393.1 YebV family protein -
HVZ90_RS09085 1851934..1853367 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T164654 NZ_CP057034:1848790-1848892 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT164654 NZ_CP057034:c1848899-1848754 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References