Detailed information of TA system TA164448

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/ParE-DnaT
• Location: 4371033..4371552
• Replicon: chromosome
• Accession: NZ_CP056899
• Organism: Citrobacter sp. RHBSTW-00017

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: HV037_RS21055
• Protein ID: WP_019078244.1
• Coordinates: 4371033..4371314 (-)
• Length: 94 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: HV037_RS21060
• Protein ID: WP_103283421.1
• Coordinates: 4371304..4371552 (-)
• Length: 83 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
HV037_RS21040	4368034..4368498	+	465	WP_016151476.1	anaerobic ribonucleoside-triphosphate reductase-activating protein	-
HV037_RS21045	4368520..4369041	-	522	WP_049270665.1	hypothetical protein	-
HV037_RS21050	4369041..4371005	-	1965	WP_103283422.1	type VI secretion system tip protein VgrG	-
HV037_RS21055	4371033..4371314	-	282	WP_019078244.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
HV037_RS21060	4371304..4371552	-	249	WP_103283421.1	plasmid stabilization protein	Antitoxin
HV037_RS21065	4371847..4372320	-	474	WP_016155556.1	hypothetical protein	-
HV037_RS21070	4372363..4374864	-	2502	WP_103283420.1	type VI secretion system ATPase TssH	-
HV037_RS21075	4374855..4375802	-	948	WP_103284439.1	type VI secretion system baseplate subunit TssG	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (6-82)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 94 a.a.
• Molecular weight: 10988.76 Da
• Isoelectric Point: 10.4466

>T164448 WP_019078244.1 NZ_CP056899:c4371314-4371033 [Citrobacter sp. RHBSTW-00017]
MTYNLEFLDIALKEWRKLSPALREQFKKKLAERLENPHVPAARLSGKLHRYKIKLRSAGYRLVYQVEDEQVVVLVIAVGR
RDGDEVYHQANRR

Nucleotide

• Length: 282 bp

>T164448 NZ_CP072933:1350690-1350956 [Xylella fastidiosa subsp. multiplex]
TTGGCCTGGACGATTGATTACACCGACACGGCCAAGCAGCAGTTACGCAAGCTCGACAAGCACATGGCACGGCGCATTGT
CGATTTCATGGATGAGCGCATCGCCGGACTAGAAAATCCACGCAGCAGTGGTAAAGCATTAACCGGACCACTTGGTGGCT
TTTGGCGTTATCGTGTTGGTGATTTTCGGGTCGTCTGCGACATTCAAGATAGCGTTTTGCGCGTCCTTGTAGTGCGTGTT
GGTCACCGGGGCGAGATTTACCGATAG

Antitoxin

Protein

• Length: 83 a.a.
• Molecular weight: 9073.37 Da
• Isoelectric Point: 4.5680

>AT164448 WP_103283421.1 NZ_CP056899:c4371552-4371304 [Citrobacter sp. RHBSTW-00017]
MPFHILTKTAASITDLKRNPMGTVNAGEGEAVAILNRNEPAFYCVPPAVYAYLLELVEDAELNRIADEREDGKRIKVSLN
DL

Nucleotide

• Length: 249 bp

>AT164448 NZ_CP072933:1350479-1350706 [Xylella fastidiosa subsp. multiplex]
ATGGCGACTTCGATTCGCCTCTCTCCTGAAATGGAGCAAAGGCTTAACTCTCTTGCCTCCCATACGGGACGCACAAAGGC
TTACTACCTGCGTGAAATCATTGAGCATGGCATTGAGGAAATGGAGGATTACTACCTTGCTGCCGATGTGTTGGAGCGTG
TCCGTCATGGACAAGAACAGGTGCATTCTGCTGCCGACGTGAGGAAAACGCTTGGCCTGGACGATTGA