Detailed information of TA system TA164429

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/ParE-DnaT
• Location: 4422573..4423092
• Replicon: chromosome
• Accession: NZ_CP056896
• Organism: Citrobacter sp. RHBSTW-00021

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: HV039_RS21340
• Protein ID: WP_019078244.1
• Coordinates: 4422573..4422854 (-)
• Length: 94 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: HV039_RS21345
• Protein ID: WP_103283421.1
• Coordinates: 4422844..4423092 (-)
• Length: 83 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
HV039_RS21325	4419574..4420038	+	465	WP_016151476.1	anaerobic ribonucleoside-triphosphate reductase-activating protein	-
HV039_RS21330	4420060..4420581	-	522	WP_049270665.1	hypothetical protein	-
HV039_RS21335	4420581..4422545	-	1965	WP_103283422.1	type VI secretion system tip protein VgrG	-
HV039_RS21340	4422573..4422854	-	282	WP_019078244.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
HV039_RS21345	4422844..4423092	-	249	WP_103283421.1	plasmid stabilization protein	Antitoxin
HV039_RS21350	4423387..4423860	-	474	WP_016155556.1	hypothetical protein	-
HV039_RS21355	4423903..4426404	-	2502	WP_103283420.1	type VI secretion system ATPase TssH	-
HV039_RS21360	4426395..4427342	-	948	WP_103284439.1	type VI secretion system baseplate subunit TssG	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (6-82)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 94 a.a.
• Molecular weight: 10988.76 Da
• Isoelectric Point: 10.4466

>T164429 WP_019078244.1 NZ_CP056896:c4422854-4422573 [Citrobacter sp. RHBSTW-00021]
MTYNLEFLDIALKEWRKLSPALREQFKKKLAERLENPHVPAARLSGKLHRYKIKLRSAGYRLVYQVEDEQVVVLVIAVGR
RDGDEVYHQANRR

Nucleotide

• Length: 282 bp

>T164429 NZ_CP072914:2135028-2135131 [Klebsiella oxytoca]
GGCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTTTTTTT

Antitoxin

Protein

• Length: 83 a.a.
• Molecular weight: 9073.37 Da
• Isoelectric Point: 4.5680

>AT164429 WP_103283421.1 NZ_CP056896:c4423092-4422844 [Citrobacter sp. RHBSTW-00021]
MPFHILTKTAASITDLKRNPMGTVNAGEGEAVAILNRNEPAFYCVPPAVYAYLLELVEDAELNRIADEREDGKRIKVSLN
DL

Nucleotide

• Length: 249 bp

>AT164429 NZ_CP072914:c2135138-2134993 [Klebsiella oxytoca]
AAAAGATAAAAAAAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCCTTATAAGAATAGTTTACCGTGTCAGGTTTTCCAGT