Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1889136..1889281 Replicon chromosome
Accession NZ_CP056878
Organism Klebsiella pneumoniae strain RHBSTW-00066

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1889172..1889274 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1889136..1889281 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HV051_RS09295 1884266..1886326 + 2061 WP_032429395.1 oligopeptidase B -
HV051_RS09300 1886330..1886989 - 660 WP_002911407.1 exodeoxyribonuclease X -
HV051_RS09305 1887068..1887298 - 231 WP_002911406.1 DNA polymerase III subunit theta -
HV051_RS09310 1887411..1887785 + 375 WP_023286640.1 CopC domain-containing protein YobA -
HV051_RS09315 1887789..1888658 + 870 WP_023286639.1 copper homeostasis membrane protein CopD -
HV051_RS09320 1888675..1889013 + 339 WP_016529031.1 YebY family protein -
- 1889136..1889281 - 146 - - Antitoxin
- 1889172..1889274 + 103 - - Toxin
HV051_RS09325 1889648..1889791 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
HV051_RS09330 1889896..1890864 - 969 WP_074194451.1 VirK/YbjX family protein -
HV051_RS09335 1891021..1891674 + 654 WP_023280291.1 protein-serine/threonine phosphatase -
HV051_RS09340 1891671..1891862 - 192 WP_002911395.1 YebW family protein -
HV051_RS09345 1891960..1892199 - 240 WP_002911393.1 YebV family protein -
HV051_RS09350 1892315..1893748 - 1434 WP_181578168.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T164373 NZ_CP056878:1889172-1889274 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT164373 NZ_CP056878:c1889281-1889136 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References