Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1888839..1888984 Replicon chromosome
Accession NZ_CP056854
Organism Klebsiella pneumoniae strain RHBSTW-00113

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1888875..1888977 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1888839..1888984 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HV075_RS09185 1883969..1886029 + 2061 WP_004151449.1 oligopeptidase B -
HV075_RS09190 1886033..1886692 - 660 WP_002911407.1 exodeoxyribonuclease X -
HV075_RS09195 1886771..1887001 - 231 WP_002911406.1 DNA polymerase III subunit theta -
HV075_RS09200 1887114..1887488 + 375 WP_004151448.1 CopC domain-containing protein YobA -
HV075_RS09205 1887492..1888361 + 870 WP_023280292.1 copper homeostasis membrane protein CopD -
HV075_RS09210 1888378..1888716 + 339 WP_002911404.1 YebY family protein -
- 1888839..1888984 - 146 - - Antitoxin
- 1888875..1888977 + 103 - - Toxin
HV075_RS09215 1889353..1889496 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
HV075_RS09220 1889601..1890569 - 969 WP_004151446.1 VirK/YbjX family protein -
HV075_RS09225 1890726..1891379 + 654 WP_023280291.1 protein-serine/threonine phosphatase -
HV075_RS09230 1891376..1891567 - 192 WP_002911395.1 YebW family protein -
HV075_RS09235 1891665..1891904 - 240 WP_032426373.1 YebV family protein -
HV075_RS09240 1892020..1893453 - 1434 WP_181586377.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T164352 NZ_CP056854:1888875-1888977 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT164352 NZ_CP056854:c1888984-1888839 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References