Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 4695310..4695845 Replicon chromosome
Accession NZ_CP056850
Organism Citrobacter freundii strain RHBSTW-00120

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag HV079_RS22565 Protein ID WP_181517643.1
Coordinates 4695558..4695845 (+) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag HV079_RS22560 Protein ID WP_137399198.1
Coordinates 4695310..4695561 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HV079_RS22530 4690322..4691170 + 849 WP_135912711.1 alpha-D-ribose 1-methylphosphonate 5-phosphate C-P-lyase PhnJ -
HV079_RS22535 4691167..4691925 + 759 WP_115259672.1 phosphonate C-P lyase system protein PhnK -
HV079_RS22540 4692034..4692714 + 681 WP_137399195.1 phosphonate C-P lyase system protein PhnL -
HV079_RS22545 4692711..4693847 + 1137 WP_181637309.1 alpha-D-ribose 1-methylphosphonate 5-triphosphate diphosphatase -
HV079_RS22550 4693850..4694395 + 546 WP_096758664.1 ribose 1,5-bisphosphokinase -
HV079_RS22555 4694468..4695226 + 759 WP_181637310.1 phosphonate metabolism protein PhnP -
HV079_RS22560 4695310..4695561 + 252 WP_137399198.1 antitoxin Antitoxin
HV079_RS22565 4695558..4695845 + 288 WP_181517643.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
HV079_RS22570 4695842..4696171 - 330 WP_096758667.1 hypothetical protein -
HV079_RS22575 4696240..4698504 - 2265 WP_181637311.1 hybrid sensor histidine kinase/response regulator -
HV079_RS22580 4698619..4700142 + 1524 WP_181637312.1 sugar ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-83)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11172.08 Da        Isoelectric Point: 10.5077

>T164329 WP_181517643.1 NZ_CP056850:4695558-4695845 [Citrobacter freundii]
MSYTVKFREDALKEWQKLDKTIQQQFAKKLKKCGENPHVPSAKLRGIKDCYKIQLRTSRFRLVYQVIDDTLVIAVVAVGK
RERSEVYNLASERLR

Download         Length: 288 bp

>T164329 NZ_CP072897:887691-887816 [Bartonella henselae]
TTGCAAGGGAACTGGAAACCACGTTGTGATCTTCATAGAGAACCAAATTGGTTGTTAATTGATAGTGTGAATGATGAATA
TGTTCATTGTGATAGAACAGGAACGCATTCTAATATGTTTAAATGA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9242.56 Da        Isoelectric Point: 4.2965

>AT164329 WP_137399198.1 NZ_CP056850:4695310-4695561 [Citrobacter freundii]
MPHIILSDTTASVSELKKNPMATVSAGDGFPVAILNRNQPAFYCVPAELYEKMLDALDDQQLVKLVHERNQQPLVDVDLD
SYL

Download         Length: 252 bp

>AT164329 NZ_CP072897:887382-887555 [Bartonella henselae]
GTGTCTGATTTTAGAGGGATTGCTTTCACTAAAGTTATTAGTGAAGAAAGATTGCCGTTTGAAATGCATATTTCTAATAC
AGAAACGCTTAAAACTTTTGAAAAAACGGACAAAGGTGAAGATATTTTTTATGCAAAAGATATAAAAGACTTTTTTAAAC
AACTCAATATTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References