Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2005678..2005823 Replicon chromosome
Accession NZ_CP056830
Organism Klebsiella pneumoniae strain RHBSTW-00128

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2005714..2005816 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2005678..2005823 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HV085_RS09700 2000808..2002868 + 2061 WP_032419805.1 oligopeptidase B -
HV085_RS09705 2002872..2003531 - 660 WP_002911407.1 exodeoxyribonuclease X -
HV085_RS09710 2003610..2003840 - 231 WP_002911406.1 DNA polymerase III subunit theta -
HV085_RS09715 2003953..2004327 + 375 WP_020316569.1 CopC domain-containing protein YobA -
HV085_RS09720 2004331..2005200 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
HV085_RS09725 2005217..2005555 + 339 WP_002911404.1 YebY family protein -
- 2005678..2005823 - 146 - - Antitoxin
- 2005714..2005816 + 103 - - Toxin
HV085_RS09730 2006191..2006334 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
HV085_RS09735 2006439..2007407 - 969 WP_014907334.1 VirK/YbjX family protein -
HV085_RS09740 2007564..2008217 + 654 WP_009484457.1 protein-serine/threonine phosphatase -
HV085_RS09745 2008214..2008405 - 192 WP_002911395.1 YebW family protein -
HV085_RS09750 2008503..2008742 - 240 WP_002911393.1 YebV family protein -
HV085_RS09755 2008858..2010291 - 1434 WP_181578701.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T164257 NZ_CP056830:2005714-2005816 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT164257 NZ_CP056830:c2005823-2005678 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References