Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) yeeUV (cbtA-cbeA)/CbtA-CbeA
Location 1260450..1261134 Replicon chromosome
Accession NZ_CP056809
Organism Citrobacter freundii strain RHBSTW-00162

Toxin (Protein)


Gene name yeeV Uniprot ID -
Locus tag HV103_RS06125 Protein ID WP_046670425.1
Coordinates 1260450..1260779 (-) Length 110 a.a.

Antitoxin (Protein)


Gene name yeeU Uniprot ID -
Locus tag HV103_RS06130 Protein ID WP_044857060.1
Coordinates 1260811..1261134 (-) Length 108 a.a.

Genomic Context

HV103_RS06120HV103_RS06125HV103_RS06130HV103_RS06135HV103_RS06140HV103_RS06145HV103_RS06150
Location: 1256182..1259724 (3543 bp)
Type: Others
Protein ID: WP_046670424.1
Location: 1260450..1260779 (330 bp)
Type: Toxin
Protein ID: WP_046670425.1
Location: 1260811..1261134 (324 bp)
Type: Antitoxin
Protein ID: WP_044857060.1
Location: 1261155..1261376 (222 bp)
Type: Others
Protein ID: WP_044857061.1
Location: 1261385..1261855 (471 bp)
Type: Others
Protein ID: WP_046670426.1
Location: 1261888..1262706 (819 bp)
Type: Others
Protein ID: WP_180976294.1
Location: 1264058..1265644 (1587 bp)
Type: Others
Protein ID: WP_046670427.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
HV103_RS061201256182..1259724-3543WP_046670424.1inverse autotransporter beta domain-containing protein-
HV103_RS061251260450..1260779-330WP_046670425.1TA system toxin CbtA family proteinToxin
HV103_RS061301260811..1261134-324WP_044857060.1type IV toxin-antitoxin system YeeU family antitoxinAntitoxin
HV103_RS061351261155..1261376-222WP_044857061.1DUF987 domain-containing protein-
HV103_RS061401261385..1261855-471WP_046670426.1DNA repair protein RadC-
HV103_RS061451261888..1262706-819WP_180976294.1DUF945 domain-containing protein-
HV103_RS061501264058..1265644-1587WP_046670427.1hypothetical protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(10-108)

Antitoxin

Antitoxin CbeA

(4-102)


Sequences

Toxin        


Download         Length: 110 a.a.        Molecular weight: 12324.13 Da        Isoelectric Point: 7.0724

>T164238 WP_046670425.1 NZ_CP056809:c1260779-1260450 [Citrobacter freundii]
MHISSVLATVSVSSHLSPVKVWQQLLTYLLEHHYGLALNDTPFHDNAAIQEHIEAGITLADAVNFLVEKYELVRIDRKGF
SWQEQTPYISVVDILRARRSTGLLKANVK

Download         Length: 330 bp

>T164238 NZ_CP072849:c2395725-2394787 [Vibrio cholerae MO10]
ATGGATAAAGATAGCCCATATTACAAACAGGTTTCCTTGCTCATAAGAATGCTTCCTGTGGTAGCAACAGAGACGGTTTT
TGCACTTAAAGGTGGCACCGCCATTAATTTATTTGTGAGAGATTTTCCTCGGTTATCTGTAGATATTGATCTTGCTTATC
TTCCACTTGAACCAAGAGATGAGGCTTTGATTAATGTCAGGGCTGCATTGCAGCGCATTACAGACAGAATCAATACTCAA
CCAGATATCAGAGCGGCATTTCAGGATAATAAAGCTGATGAACTGAGAATAGTTGTATCAAGTCCGGTTGCGACGATCAA
AATTGAAGTGTCGCCCGTCGCCAGAGGTACATTGCATAGTGCAGAAATAATGCCAGTTCAAGAGTCTGTTGAAGACGAGT
TTGGTTATGCTGAGATTCAGGTAGTCAGTCTTCCCGATCTGTATGGTGGGAAATTGTGTGCTGCAATGGATCGCCAACAT
CCTCGCGACTTATTTGATGTGCGTATGTTACTTGGCAGTGAAGGGATTTCGAGAGAGATTTTGGTGGGTTTTTTAACCTA
TACATTAAGTCACCCTCGGCCTATTAATGAAGTCATGTCGCCAAACTGGCAGCCTCTGAATGAGAAATTTCAGGCAGAAT
TTGACGGAATGACTTTTGAAAAAGTTGAATGCGAAGACTTAGCCTCTGTTAGGCCCATGATGTTAATTGAACTGCAAAAA
CATTTCACAGAAAGGGATCATGCTTTCCTTATGTCATTCAAAAGAGGGCAACCTGACTGGGCATTGTTTGACTATCCTAA
TGCAGCAGACTTGCCAGCGATTCGTTGGAAATTGCAGAACATTAACAAATTGGCAAAGAATCAAGCAAAACACCAAGAGC
AATTAGATAAATTGAAGCAAGTGCTTGATGATTGGCTTGTTAACGCAAACGCCGAGTAA

Antitoxin


Download         Length: 108 a.a.        Molecular weight: 11977.77 Da        Isoelectric Point: 7.3237

>AT164238 WP_044857060.1 NZ_CP056809:c1261134-1260811 [Citrobacter freundii]
MQNSWGLKRDISPCFGARLVQEGCRLHFLADRAGISGTFNEEEALRLNKAFPLVMKQLELMLSSGELNPRHQHCVTLYHN
GLICEADTLGSHGYVYIVIYPQASATK

Download         Length: 324 bp

>AT164238 NZ_CP072849:c2396509-2395718 [Vibrio cholerae MO10]
ATGTCATCTAAAATAAACTGGCTTGTTGCTCATACTTCTCCTGGTGCGCTAGTACTTCAGCAATGGCTGACTGAAAACGG
CGTGAGCTACTCGTTGGCTCAAAAGTACGCGCAGAACGGTTGGCTGAAGAAGCTTAGTTCTGGTGTGTACTATCGTCCAA
ATGCGCAGGGCGATATAAAGCCAACTTGGGTTGATGCCATTCAAGCATTGGATGTGCAATTGGGCGTTCCAGTTCATTTG
GCTGGATTGAGCAGCTTAACTCACCAAGGACTGAGTCACTATTTACAGCTGAACAAAGAGCAAGTTTGGATTTGCGTTAA
AAACAAGTCGTCCTTACCGAAATGGTTTCGTGAATTCCCTTATCAGAATTGGTTTTACTGCGGAAACCATAAGCTTGAAG
TGAATCCCGAGAAAGATTTGAAAAGGATCACGGTTAAAGAGAAAGAGCTCACTGTCAGCTGTGCAGAACTTGCTGCCTAT
GAAGTGGTAGATGCGATTGGAAAGCTGATTTCATTTGAGCATGTCGCAGAATTATTTCAGGGTTTAGTCAATCTTAGCCC
TAGAAAAGTACAAGATATTCTTGAACGAAGCAGCTCTGTTCAGGCAAACCGAATATTTCTATTTCTGGGTCGATACTACG
ATCACCAGTGGGTCAATCGCATAGATGAAACAAGAATTAAATTGGGGGCAGGAAAGCGGCAGGTTGTCGAAAAAGGACGT
TTTGATGAGCGATATCAAATCACAGTGCCAGAGATATTAAGCGTCAAAAAAGGTGAACAACATAATGGATAA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References