164238

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) yeeUV (cbtA-cbeA)/CbtA-CbeA
Location 1260450..1261134 Replicon chromosome
Accession NZ_CP056809
Organism Citrobacter freundii strain RHBSTW-00162

Toxin (Protein)


Gene name yeeV Uniprot ID -
Locus tag HV103_RS06125 Protein ID WP_046670425.1
Coordinates 1260450..1260779 (-) Length 110 a.a.

Antitoxin (Protein)


Gene name yeeU Uniprot ID -
Locus tag HV103_RS06130 Protein ID WP_044857060.1
Coordinates 1260811..1261134 (-) Length 108 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HV103_RS06120 1256182..1259724 - 3543 WP_046670424.1 inverse autotransporter beta domain-containing protein -
HV103_RS06125 1260450..1260779 - 330 WP_046670425.1 TA system toxin CbtA family protein Toxin
HV103_RS06130 1260811..1261134 - 324 WP_044857060.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
HV103_RS06135 1261155..1261376 - 222 WP_044857061.1 DUF987 domain-containing protein -
HV103_RS06140 1261385..1261855 - 471 WP_046670426.1 DNA repair protein RadC -
HV103_RS06145 1261888..1262706 - 819 WP_180976294.1 DUF945 domain-containing protein -
HV103_RS06150 1264058..1265644 - 1587 WP_046670427.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(10-108)

Antitoxin

Antitoxin CbeA

(4-102)


Sequences

Toxin        


Download         Length: 110 a.a.        Molecular weight: 12324.13 Da        Isoelectric Point: 7.0724

>T164238 WP_046670425.1 NZ_CP056809:c1260779-1260450 [Citrobacter freundii]
MHISSVLATVSVSSHLSPVKVWQQLLTYLLEHHYGLALNDTPFHDNAAIQEHIEAGITLADAVNFLVEKYELVRIDRKGF
SWQEQTPYISVVDILRARRSTGLLKANVK

Download         Length: 330 bp

>T164238 NZ_CP072849:c2395725-2394787 [Vibrio cholerae MO10]
ATGGATAAAGATAGCCCATATTACAAACAGGTTTCCTTGCTCATAAGAATGCTTCCTGTGGTAGCAACAGAGACGGTTTT
TGCACTTAAAGGTGGCACCGCCATTAATTTATTTGTGAGAGATTTTCCTCGGTTATCTGTAGATATTGATCTTGCTTATC
TTCCACTTGAACCAAGAGATGAGGCTTTGATTAATGTCAGGGCTGCATTGCAGCGCATTACAGACAGAATCAATACTCAA
CCAGATATCAGAGCGGCATTTCAGGATAATAAAGCTGATGAACTGAGAATAGTTGTATCAAGTCCGGTTGCGACGATCAA
AATTGAAGTGTCGCCCGTCGCCAGAGGTACATTGCATAGTGCAGAAATAATGCCAGTTCAAGAGTCTGTTGAAGACGAGT
TTGGTTATGCTGAGATTCAGGTAGTCAGTCTTCCCGATCTGTATGGTGGGAAATTGTGTGCTGCAATGGATCGCCAACAT
CCTCGCGACTTATTTGATGTGCGTATGTTACTTGGCAGTGAAGGGATTTCGAGAGAGATTTTGGTGGGTTTTTTAACCTA
TACATTAAGTCACCCTCGGCCTATTAATGAAGTCATGTCGCCAAACTGGCAGCCTCTGAATGAGAAATTTCAGGCAGAAT
TTGACGGAATGACTTTTGAAAAAGTTGAATGCGAAGACTTAGCCTCTGTTAGGCCCATGATGTTAATTGAACTGCAAAAA
CATTTCACAGAAAGGGATCATGCTTTCCTTATGTCATTCAAAAGAGGGCAACCTGACTGGGCATTGTTTGACTATCCTAA
TGCAGCAGACTTGCCAGCGATTCGTTGGAAATTGCAGAACATTAACAAATTGGCAAAGAATCAAGCAAAACACCAAGAGC
AATTAGATAAATTGAAGCAAGTGCTTGATGATTGGCTTGTTAACGCAAACGCCGAGTAA

Antitoxin


Download         Length: 108 a.a.        Molecular weight: 11977.77 Da        Isoelectric Point: 7.3237

>AT164238 WP_044857060.1 NZ_CP056809:c1261134-1260811 [Citrobacter freundii]
MQNSWGLKRDISPCFGARLVQEGCRLHFLADRAGISGTFNEEEALRLNKAFPLVMKQLELMLSSGELNPRHQHCVTLYHN
GLICEADTLGSHGYVYIVIYPQASATK

Download         Length: 324 bp

>AT164238 NZ_CP072849:c2396509-2395718 [Vibrio cholerae MO10]
ATGTCATCTAAAATAAACTGGCTTGTTGCTCATACTTCTCCTGGTGCGCTAGTACTTCAGCAATGGCTGACTGAAAACGG
CGTGAGCTACTCGTTGGCTCAAAAGTACGCGCAGAACGGTTGGCTGAAGAAGCTTAGTTCTGGTGTGTACTATCGTCCAA
ATGCGCAGGGCGATATAAAGCCAACTTGGGTTGATGCCATTCAAGCATTGGATGTGCAATTGGGCGTTCCAGTTCATTTG
GCTGGATTGAGCAGCTTAACTCACCAAGGACTGAGTCACTATTTACAGCTGAACAAAGAGCAAGTTTGGATTTGCGTTAA
AAACAAGTCGTCCTTACCGAAATGGTTTCGTGAATTCCCTTATCAGAATTGGTTTTACTGCGGAAACCATAAGCTTGAAG
TGAATCCCGAGAAAGATTTGAAAAGGATCACGGTTAAAGAGAAAGAGCTCACTGTCAGCTGTGCAGAACTTGCTGCCTAT
GAAGTGGTAGATGCGATTGGAAAGCTGATTTCATTTGAGCATGTCGCAGAATTATTTCAGGGTTTAGTCAATCTTAGCCC
TAGAAAAGTACAAGATATTCTTGAACGAAGCAGCTCTGTTCAGGCAAACCGAATATTTCTATTTCTGGGTCGATACTACG
ATCACCAGTGGGTCAATCGCATAGATGAAACAAGAATTAAATTGGGGGCAGGAAAGCGGCAGGTTGTCGAAAAAGGACGT
TTTGATGAGCGATATCAAATCACAGTGCCAGAGATATTAAGCGTCAAAAAAGGTGAACAACATAATGGATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References