Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-yefM/YoeB-RelB
Location 5929221..5929738 Replicon chromosome
Accession NZ_CP056775
Organism Dyadobacter sp. Q3-56

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag HWI92_RS24600 Protein ID WP_204660053.1
Coordinates 5929221..5929481 (-) Length 87 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag HWI92_RS24605 Protein ID WP_204660054.1
Coordinates 5929478..5929738 (-) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HWI92_RS24580 5925405..5926436 - 1032 WP_204660049.1 N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase -
HWI92_RS24585 5926680..5927315 + 636 WP_204660050.1 ATP-binding cassette domain-containing protein -
HWI92_RS24590 5927306..5928379 + 1074 WP_204660051.1 hypothetical protein -
HWI92_RS24595 5928419..5929132 - 714 WP_204660052.1 SDR family oxidoreductase -
HWI92_RS24600 5929221..5929481 - 261 WP_204660053.1 Txe/YoeB family addiction module toxin Toxin
HWI92_RS24605 5929478..5929738 - 261 WP_204660054.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
HWI92_RS24610 5929861..5930607 + 747 WP_204660055.1 3-oxoacyl-[acyl-carrier-protein] reductase -
HWI92_RS24615 5930681..5932753 + 2073 WP_204660056.1 VWA domain-containing protein -
HWI92_RS24620 5932757..5933719 + 963 WP_204660057.1 DUF2279 domain-containing protein -
HWI92_RS24625 5933730..5934701 + 972 WP_204660058.1 DUF2027 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(1-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-72)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 10656.12 Da        Isoelectric Point: 8.0254

>T164189 WP_204660053.1 NZ_CP056775:c5929481-5929221 [Dyadobacter sp. Q3-56]
MKIVFSENAWDDYKSWQEEDKKMAKRINDLIKDIQRHPFEGIGKPEPLKFDFKGYWSRRIDQEHRLVYKIENDSLLIYAC
RYHYDR

Download         Length: 261 bp

>T164189 NZ_CP072825:c5128455-5128171 [Klebsiella pneumoniae]
ATGACCTATAAGCTGGCCTTTAATGAATCAGCTCTGAAAGAATGGAAAAAATTGGGCCATACCATTCGGGAACAATTCAA
AAAGAAGCTCGCTGAGCGCCTGTTGAACCCACGGGTGCCCGCATCGCAACTCCATGGACGCAAAGACCAGTACAAAATAA
AGCTCCGTGGCGCAGGCTACCGACTGGTTTGCAGTGTCAACGATGATGTTGTAACGGTCACCGTAATTGGCGTCGGTAAA
CGTGAGAATGATGATATTTACAATTTGACCAAACACAGAAATTAA

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9767.05 Da        Isoelectric Point: 4.8428

>AT164189 WP_204660054.1 NZ_CP056775:c5929738-5929478 [Dyadobacter sp. Q3-56]
MIAANYTEFRNGLKKFLDEVEENHETLIVKRGTGKGTVVISLDEYNSMLETMHLLSSKKNAERLYESVSQMNTGKTITLD
ELPSEQ

Download         Length: 261 bp

>AT164189 NZ_CP072825:c5128693-5128445 [Klebsiella pneumoniae]
ATGGCATTTCAGGTACTAACCACTACTGCAGCAAGCATCACAGAGCTTAAACGTGATCCTATGGGCACCTTCAATGCAGG
AGAAGGTGCCCCGGTAGCCATACTGAATCGCAACGAACCCGCTTTTTACTGTGTACCGCCTGCTCTGTATGCTCAACTGA
TGGAGCTTCTTGAAGATCAGGAGCTGGGTCATATTGCTGATGAGCGAATTGGTGAGGCGGTAATCGAGGTCAGTCTAGAT
GACCTATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References