Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2198131..2198299 Replicon chromosome
Accession NZ_CP056760
Organism Klebsiella grimontii strain RHBSTW-00186

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2198189..2198292 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2198131..2198299 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HV114_RS10640 2193257..2195317 + 2061 WP_064342867.1 oligopeptidase B -
HV114_RS10645 2195324..2195983 - 660 WP_004134816.1 exodeoxyribonuclease X -
HV114_RS10650 2196062..2196292 - 231 WP_004103351.1 DNA polymerase III subunit theta -
HV114_RS10655 2196428..2196802 + 375 WP_004134817.1 CopC domain-containing protein YobA -
HV114_RS10660 2196807..2197676 + 870 WP_004134819.1 copper homeostasis membrane protein CopD -
HV114_RS10665 2197693..2198031 + 339 WP_004103344.1 YebY family protein -
- 2198131..2198299 - 169 - - Antitoxin
- 2198189..2198292 + 104 - - Toxin
HV114_RS10670 2198417..2199376 - 960 WP_049085573.1 spore coat U domain-containing protein -
HV114_RS10675 2199391..2201721 - 2331 WP_049089570.1 fimbrial biogenesis outer membrane usher protein -
HV114_RS10680 2201724..2202488 - 765 WP_004134823.1 molecular chaperone -
HV114_RS10685 2202507..2203025 - 519 WP_049099811.1 spore coat U domain-containing protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2125671..2221182 95511


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T164169 NZ_CP056760:2198189-2198292 [Klebsiella grimontii]
GGCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 169 bp

>AT164169 NZ_CP056760:c2198299-2198131 [Klebsiella grimontii]
AATAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCCTTATAAGAATAGTTTACCGTGTCAGGTTTTCCAGTCCGTGACAAAAGTG
GACGAATAA

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References