164164

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 3814386..3815043 Replicon chromosome
Accession NZ_CP056756
Organism Enterobacter hormaechei strain RHBSTW-00198

Toxin (Protein)


Gene name cptA Uniprot ID A0A179PSF7
Locus tag HV117_RS18310 Protein ID WP_017382887.1
Coordinates 3814386..3814796 (-) Length 137 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID G8LDB7
Locus tag HV117_RS18315 Protein ID WP_003863437.1
Coordinates 3814777..3815043 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HV117_RS18290 3810384..3812117 - 1734 WP_047050807.1 single-stranded-DNA-specific exonuclease RecJ -
HV117_RS18295 3812123..3812836 - 714 WP_003863443.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
HV117_RS18300 3812865..3813761 - 897 WP_047050805.1 site-specific tyrosine recombinase XerD -
HV117_RS18305 3813863..3814384 + 522 WP_015571793.1 flavodoxin FldB -
HV117_RS18310 3814386..3814796 - 411 WP_017382887.1 protein YgfX Toxin
HV117_RS18315 3814777..3815043 - 267 WP_003863437.1 FAD assembly factor SdhE Antitoxin
HV117_RS18320 3815338..3816318 + 981 WP_022649306.1 tRNA-modifying protein YgfZ -
HV117_RS18325 3816430..3817089 - 660 WP_047050804.1 hemolysin III family protein -
HV117_RS18330 3817356..3818087 + 732 WP_047050802.1 MurR/RpiR family transcriptional regulator -
HV117_RS18335 3818204..3819637 + 1434 WP_023295383.1 6-phospho-beta-glucosidase BglA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-132)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 137 a.a.        Molecular weight: 16321.21 Da        Isoelectric Point: 11.4775

>T164164 WP_017382887.1 NZ_CP056756:c3814796-3814386 [Enterobacter hormaechei]
VVLWQSDLRVSWRSQWMSLLLHGLVAALVLLVPWPLSYTPLWLLLLSFVVFDSVRSQRRINARQGEIKLLMDSRLRWQGK
EWEMMGTPWMLNTGMMLRLRRVEDNRRQHLWLAADSMDPAEWRDLRRLIVQQPTQE

Download         Length: 411 bp

>T164164 NZ_CP072802:3226414-3226521 [Escherichia coli]
ATGACGCTCGCAGAACTGGGCATGGCCTTCTGGCATGATTTAGCGGCTCCGGTCATTGCTGGCATTCTTGCCAGTATGAT
CGTGAACTGGCTGAACAAGCGGAAGTAA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10526.96 Da        Isoelectric Point: 4.8310

>AT164164 WP_003863437.1 NZ_CP056756:c3815043-3814777 [Enterobacter hormaechei]
MDINNKARIHWACRRGMRELDISIMPFFEYEYDSLSDDDKRLFVRLLESDDPDLFNWLMNHGKPADTELQRMVQLIQTRN
QERGPVAI

Download         Length: 267 bp

>AT164164 NZ_CP072802:c3226357-3226300 [Escherichia coli]
TCAAGAATGGCCCCCGTGATGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A179PSF7

Antitoxin

Source ID Structure
AlphaFold DB A0A837F8P5

References