Detailed information of TA system
Overview
TA module
| Type | IV | Classification (family/domain) | yfjZ-ypjF/CbtA-CbeA |
| Location | 3976512..3977221 | Replicon | chromosome |
| Accession | NZ_CP056747 | ||
| Organism | Enterobacter hormaechei strain RHBSTW-00217 | ||
Toxin (Protein)
| Gene name | ypjF | Uniprot ID | A0A7D6YAQ1 |
| Locus tag | HV129_RS18860 | Protein ID | WP_071886833.1 |
| Coordinates | 3976512..3976880 (-) | Length | 123 a.a. |
Antitoxin (Protein)
| Gene name | yfjZ | Uniprot ID | - |
| Locus tag | HV129_RS18865 | Protein ID | WP_047051179.1 |
| Coordinates | 3976901..3977221 (-) | Length | 107 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| HV129_RS18840 | 3972443..3972937 | + | 495 | WP_047051176.1 | oxidoreductase | - |
| HV129_RS18845 | 3972955..3974892 | + | 1938 | WP_063842269.1 | bifunctional diguanylate cyclase/phosphodiesterase | - |
| HV129_RS18850 | 3975152..3975409 | + | 258 | WP_003863178.1 | YjhX family toxin | - |
| HV129_RS18855 | 3975420..3976166 | + | 747 | WP_047051178.1 | class I SAM-dependent methyltransferase | - |
| HV129_RS18860 | 3976512..3976880 | - | 369 | WP_071886833.1 | TA system toxin CbtA family protein | Toxin |
| HV129_RS18865 | 3976901..3977221 | - | 321 | WP_047051179.1 | type IV toxin-antitoxin system YeeU family antitoxin | Antitoxin |
| HV129_RS18870 | 3977239..3977460 | - | 222 | WP_016243789.1 | DUF987 domain-containing protein | - |
| HV129_RS18875 | 3977469..3977951 | - | 483 | WP_075211782.1 | DNA repair protein RadC | - |
| HV129_RS18880 | 3977960..3978418 | - | 459 | WP_047051181.1 | antirestriction protein | - |
| HV129_RS18885 | 3978498..3978734 | - | 237 | WP_047051182.1 | DUF905 domain-containing protein | - |
| HV129_RS18890 | 3978811..3979221 | - | 411 | WP_047051183.1 | hypothetical protein | - |
| HV129_RS18895 | 3979310..3979924 | - | 615 | WP_047051184.1 | hypothetical protein | - |
| HV129_RS18900 | 3979921..3980625 | - | 705 | WP_047051185.1 | WYL domain-containing protein | - |
| HV129_RS18905 | 3980827..3981661 | - | 835 | Protein_3690 | DUF945 domain-containing protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 123 a.a. Molecular weight: 13738.90 Da Isoelectric Point: 8.1347
>T164118 WP_071886833.1 NZ_CP056747:c3976880-3976512 [Enterobacter hormaechei]
MKTLPATISRAAKPCLSPVAVWQMLLTRLLEKHYGLTLNDTPFCDQTVIQEHIDAGITLANAVNFLVEKYELVRIDRTGF
TSQEQAPYLTVTDILHARRACGLMNSCSYREVSNIVLSRSRQ
MKTLPATISRAAKPCLSPVAVWQMLLTRLLEKHYGLTLNDTPFCDQTVIQEHIDAGITLANAVNFLVEKYELVRIDRTGF
TSQEQAPYLTVTDILHARRACGLMNSCSYREVSNIVLSRSRQ
Download Length: 369 bp
>T164118 NZ_CP072793:c1296208-1295630 [Thiothrix unzii]
ATGCTTTCAGGTCAAAATTTTACAGTTTTGTACGATGCCTGTGTGCTTTATCCAGCACCCTTGCGTGATTTTCTGGTGCG
GTTGGCGTGGACGGGTGTATTTCGGGCAAAATGGACGCAACAAATTCATGAAGAATGGATATGCAACGCTTTACAGAACA
ACACCAAGCTGACCCGTGAACGTTTGGAAATGACTGCTGGTAAGATGAATGCTGCAATTATGGATTCACTGGTATCAGGT
TATGAACCACTTATTGCTGGTTTAGAATTGCCCGATGTGAATGACAGGCATGTATTAGCTGCGGCGATTAAGGGGCAAGC
AGAAGTTATTGTCACGTTTAATCTGAAAGACTTTCCTGCTAGTTACCTAAAACCCTTCGGTATTTTGGCACAGCACCCTG
ATGAGTTTATCAGCCACCTGACTAATCTATACCCCGAAATGATTTTACTGACTGCCCGACAACAAAGGGCGAGCTTGAAA
AATCCACCAAGAACTGTCGATGAATTCTTAGATACATTGTTGCGTCAACAGTTGCCCCGCACAGCGGCATTCCTTAAGCA
ACGTAAGGAGCTTATCTGA
ATGCTTTCAGGTCAAAATTTTACAGTTTTGTACGATGCCTGTGTGCTTTATCCAGCACCCTTGCGTGATTTTCTGGTGCG
GTTGGCGTGGACGGGTGTATTTCGGGCAAAATGGACGCAACAAATTCATGAAGAATGGATATGCAACGCTTTACAGAACA
ACACCAAGCTGACCCGTGAACGTTTGGAAATGACTGCTGGTAAGATGAATGCTGCAATTATGGATTCACTGGTATCAGGT
TATGAACCACTTATTGCTGGTTTAGAATTGCCCGATGTGAATGACAGGCATGTATTAGCTGCGGCGATTAAGGGGCAAGC
AGAAGTTATTGTCACGTTTAATCTGAAAGACTTTCCTGCTAGTTACCTAAAACCCTTCGGTATTTTGGCACAGCACCCTG
ATGAGTTTATCAGCCACCTGACTAATCTATACCCCGAAATGATTTTACTGACTGCCCGACAACAAAGGGCGAGCTTGAAA
AATCCACCAAGAACTGTCGATGAATTCTTAGATACATTGTTGCGTCAACAGTTGCCCCGCACAGCGGCATTCCTTAAGCA
ACGTAAGGAGCTTATCTGA
Antitoxin
Download Length: 107 a.a. Molecular weight: 11901.60 Da Isoelectric Point: 7.2633
>AT164118 WP_047051179.1 NZ_CP056747:c3977221-3976901 [Enterobacter hormaechei]
MRSNATWGLQRDITPRLGARLVQEGNRLHYLADRASITGKFSDAECLKLDVAFPHFISLMESMLTTGEMNPRHAHCVTLY
RNGFTCEADTLGSCGYLYIVVYPTQS
MRSNATWGLQRDITPRLGARLVQEGNRLHYLADRASITGKFSDAECLKLDVAFPHFISLMESMLTTGEMNPRHAHCVTLY
RNGFTCEADTLGSCGYLYIVVYPTQS
Download Length: 321 bp
>AT164118 NZ_CP072793:c1296654-1296208 [Thiothrix unzii]
ATGCCTGCCTTAGTCAGTTATCAAGTCCCGACGCAAGAAGATACCGAGCTTGCTGTTGAGAGCAGCCGTTTGTTGGCTGC
TTGCATTGGCAAAGGAGAAAGTGCTTGTTTACGCCTTCATAACGGCAATGAACTGCTGCAAGTTCCCGTAAAAGCTATTC
GCTTGTTGGTGGACATTTTGGATGCAATGGCGCGGGGTGATGCCGTATCTCTCATTCCGATCCACAAAGAATTGACCACC
CAAGAAGCAGCTAACATCTTAAATGTTTCACGTCCCTATTTAGTAAAGTTGATAGAAGCTGGGGAAATACCATTTCATAA
GAATGGAGTACGTCGTCGCGTTTTCTTTAAAGACTTAATGGAGTACAAGCAAAAACGGGATCAGGCCAGTATGCTGCTAC
TGGATGAGTTGACTGCCGAAGCCCAAGAATTTGAGATGGGTTACTAA
ATGCCTGCCTTAGTCAGTTATCAAGTCCCGACGCAAGAAGATACCGAGCTTGCTGTTGAGAGCAGCCGTTTGTTGGCTGC
TTGCATTGGCAAAGGAGAAAGTGCTTGTTTACGCCTTCATAACGGCAATGAACTGCTGCAAGTTCCCGTAAAAGCTATTC
GCTTGTTGGTGGACATTTTGGATGCAATGGCGCGGGGTGATGCCGTATCTCTCATTCCGATCCACAAAGAATTGACCACC
CAAGAAGCAGCTAACATCTTAAATGTTTCACGTCCCTATTTAGTAAAGTTGATAGAAGCTGGGGAAATACCATTTCATAA
GAATGGAGTACGTCGTCGCGTTTTCTTTAAAGACTTAATGGAGTACAAGCAAAAACGGGATCAGGCCAGTATGCTGCTAC
TGGATGAGTTGACTGCCGAAGCCCAAGAATTTGAGATGGGTTACTAA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|