Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /RES-TIGR02293
Location 3385194..3386107 Replicon chromosome
Accession NZ_CP056747
Organism Enterobacter hormaechei strain RHBSTW-00217

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag HV129_RS16105 Protein ID WP_047052345.1
Coordinates 3385634..3386107 (+) Length 158 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag HV129_RS16100 Protein ID WP_047052347.1
Coordinates 3385194..3385637 (+) Length 148 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HV129_RS16085 3380268..3381989 + 1722 WP_003858307.1 cysteine/glutathione ABC transporter ATP-binding protein/permease CydC -
HV129_RS16090 3382035..3382739 + 705 Protein_3141 leucyl/phenylalanyl-tRNA--protein transferase -
HV129_RS16095 3383024..3383242 + 219 WP_002211347.1 translation initiation factor IF-1 -
HV129_RS16100 3385194..3385637 + 444 WP_047052347.1 DUF2384 domain-containing protein Antitoxin
HV129_RS16105 3385634..3386107 + 474 WP_047052345.1 RES domain-containing protein Toxin
HV129_RS16110 3386130..3386684 - 555 WP_047052344.1 type I-F CRISPR-associated endoribonuclease Cas6/Csy4 -
HV129_RS16115 3386694..3387692 - 999 WP_047052342.1 type I-F CRISPR-associated protein Csy3 -
HV129_RS16120 3387706..3388641 - 936 WP_047052340.1 type I-F CRISPR-associated protein Csy2 -
HV129_RS16125 3388638..3389948 - 1311 WP_047052339.1 type I-F CRISPR-associated protein Csy1 -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RES domain

(3-148)

Antitoxin

Antitoxin Xre/MbcA/ParS-like, toxin-binding domain

(94-144)


Sequences

Toxin        


Download         Length: 158 a.a.        Molecular weight: 17570.95 Da        Isoelectric Point: 5.1151

>T164116 WP_047052345.1 NZ_CP056747:3385634-3386107 [Enterobacter hormaechei]
MIFYRLVTGRFASEAWSGSGANQYGGRWNHKGHPAVYVSTSISLASLEILVHVRKDTVLNQYQLFSINIPDDQIDYLDKA
WLPEDWQENPAPVSTMDLGTGWLQANSALALILPSCIIPYENNAILNPLHPAFRKALNSVELLPFDFDTRLAEKTAP

Download         Length: 474 bp

>T164116 NZ_CP072793:350320-350577 [Thiothrix unzii]
ATGCGAATAATCTTTTCATCCAAAGCGTGGGAGGATTACGGGCATTGGCAACAAGCCGATAAGAAAATTCTCAAGCGTAT
CAATGATCTGATCAAAGCGATTTCGCGTGAACCGTTCGAGGGTATCGGCAAGCCCGAACCATTGCGGCACGGGCTTTCTG
GCTATTGGTCACGCCGTATCAATGATGAACATCGGCTGGTCTACAAAGTGGAAGGGGAAGACTTGCTGATAGCGATGTGC
CGCTATCACTACCCGTAG

Antitoxin


Download         Length: 148 a.a.        Molecular weight: 16502.77 Da        Isoelectric Point: 6.4819

>AT164116 WP_047052347.1 NZ_CP056747:3385194-3385637 [Enterobacter hormaechei]
MRTWVPAQRSADNTLWRYAGLPASRGMRLIEYLNQGLPVSVLDNIHEWTDMSKAEILRVTGINERNVARRKSTGRTLTPD
ESERVARFVRVLDAAVDYFGSKEEAWNWLQLPVRGLGNVAPVDLIATETGALEVTDLIGRLEHGVFA

Download         Length: 444 bp

>AT164116 NZ_CP072793:350072-350329 [Thiothrix unzii]
ATGAACGCCATTTCCTACACCGCTGTGCGAGCGGATCTCGCCAAAACGATGGATCGGGTCTGCGAAGACCATGAACCCGT
CATTATTACCCGCAACCGCGATCAAGCCGTGGTGATGATTTCGCTGGAAGATTACAAAGCGATGGAAGAAACCGCGTATT
TATTGCGTAGTCCAGCCAATGCCAGCCGCTTGCTGGAGTCCATTGCGGAATTGGAGCGTGGTCAAGGGCAAGTGCGTGAG
TTGATCGAATGCGAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References