Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 2711653..2712392 Replicon chromosome
Accession NZ_CP056747
Organism Enterobacter hormaechei strain RHBSTW-00217

Toxin (Protein)


Gene name tacT Uniprot ID -
Locus tag HV129_RS12855 Protein ID WP_045329830.1
Coordinates 2711907..2712392 (+) Length 162 a.a.

Antitoxin (Protein)


Gene name tacA Uniprot ID -
Locus tag HV129_RS12850 Protein ID WP_047050951.1
Coordinates 2711653..2711919 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HV129_RS12830 2707130..2708116 + 987 WP_047050955.1 DUF979 domain-containing protein -
HV129_RS12835 2708126..2709121 + 996 WP_047050954.1 DUF2891 domain-containing protein -
HV129_RS12840 2709143..2710530 - 1388 Protein_2499 MFS transporter -
HV129_RS12845 2710660..2711589 + 930 WP_047050986.1 LysR family transcriptional regulator -
HV129_RS12850 2711653..2711919 + 267 WP_047050951.1 DUF1778 domain-containing protein Antitoxin
HV129_RS12855 2711907..2712392 + 486 WP_045329830.1 GNAT family N-acetyltransferase Toxin
HV129_RS12860 2712570..2713862 - 1293 WP_047050950.1 glycoside hydrolase -
HV129_RS12865 2713967..2714725 - 759 WP_015570520.1 DeoR/GlpR family DNA-binding transcription regulator -
HV129_RS12870 2714812..2715396 + 585 WP_047050949.1 NUDIX domain-containing protein -
HV129_RS12875 2715481..2716239 + 759 WP_047050948.1 trans-aconitate 2-methyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(58-151)

Antitoxin

Vibrio phage ICP1, Orf50

(2-87)


Sequences

Toxin        


Download         Length: 162 a.a.        Molecular weight: 17512.18 Da        Isoelectric Point: 9.9658

>T164114 WP_045329830.1 NZ_CP056747:2711907-2712392 [Enterobacter hormaechei]
VGRVTAPEPLSSAHQLAEFVSGEAVLDEWLKQRGLKNQALGAARTFVVCKTGTKQVAGFYSLATGSVNHTQATGNLRRNM
PDPIPVIILARLAVDVSLRGNGLGADLLHDAVLRCYRVAENIGVRAIMVHALTEEAKAFYIHHGFKASQTQERTLFLRLP
Q

Download         Length: 486 bp

>T164114 NZ_CP072791:c1233488-1232742 [Bacillus velezensis]
ATGCTTTTGTTTTTTCAGATCATGGTGTGGACGATGGCGGCCGCACTCATTTTATATGTGTACGCATCCTGGCGGTATGA
AGCAAAGGTAAAAGAAAAAATGTTTGCCATCCGTAAAACGTGGTATTTACTATTTGTAGTAGGCGCCATGGTCTATTGGA
CATATGATCCCGAATCGCTCTTTGCCGCATGGAGACAATATTTGATTGTTGCCGTCTGCTTTGCCCTTATTGATGCGTTT
ATCTTTTTGAGCGCGTATATCAAAAAGCTCGCCGGCAATGAATTAGAGACGGATACGCGGGAAATTTTAGAAGAAAATAA
CGAAATGCTTCACTCCTATCTTGAAAAACTGAAAACCTATCAATATCTGTTGAAAAATGAACCGATCCATGTATATTATG
GAAGTACAGAAGCTTATGCGGAAGGCATCAGCAGACTGCTGGCCGCTTATGGAGAAAAAATGAATGTCACGGCTTCCTTG
TGCGAGTATTCCGCACAATCGGATAAGGACCGCTTGACGGAGCATATGCCTGATGCGGCGGACGTTCAGTCCCGTCTTAA
CCGTAAAGACGTCTACTATGATCAAAAAGGCAGGCTTGTGCTTATTCCGTTTACAGTCCAGGACCGCCATTACGTGATCA
AACTCACGTCGGAAAACCTGTTGACGGAATTCGATTATTTGCTTTTCACATCGCTAACGAGCATTTATGATTTAATGCTG
CCAATAGAAGAGGAAGGTGACGGTTAA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10089.51 Da        Isoelectric Point: 4.4857

>AT164114 WP_047050951.1 NZ_CP056747:2711653-2711919 [Enterobacter hormaechei]
MKSDVQLNLRAKESQRALIDAAAEILHKSRTDFILEMACQAAENVILDRRVFNFNDEQYAEFIDMLDAPVANDPAIEKLL
ARKPQWDV

Download         Length: 267 bp

>AT164114 NZ_CP072791:c1232741-1232571 [Bacillus velezensis]
ATGGAGCAGGCATTTCAAAACGGGCAGCCGGAACAAAGAGCGAAACCGTTCAAAATGTTTAAAAAACGTTCAATGACAAG
TATCGCAAGTTACCAGGTCAGCCCTCATACCGCCAGAATTTTCAAAGAAAACGAGCGGCTGATTGACAAGTATAAACAAA
AAAAAGCTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References