Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) yeeUV (cbtA-cbeA)/CbtA-CbeA
Location 1532573..1533251 Replicon chromosome
Accession NZ_CP056747
Organism Enterobacter hormaechei strain RHBSTW-00217

Toxin (Protein)


Gene name yeeV Uniprot ID A0A9K1QZI5
Locus tag HV129_RS07260 Protein ID WP_032949840.1
Coordinates 1532573..1532896 (-) Length 108 a.a.

Antitoxin (Protein)


Gene name yeeU Uniprot ID A0A9K1QZR3
Locus tag HV129_RS07265 Protein ID WP_032642918.1
Coordinates 1532928..1533251 (-) Length 108 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HV129_RS07245 1528773..1529672 - 900 WP_045339512.1 carbohydrate ABC transporter permease -
HV129_RS07250 1529672..1530649 - 978 WP_080350787.1 sugar ABC transporter permease -
HV129_RS07255 1530717..1531955 - 1239 WP_047729546.1 ribokinase -
HV129_RS07260 1532573..1532896 - 324 WP_032949840.1 TA system toxin CbtA family protein Toxin
HV129_RS07265 1532928..1533251 - 324 WP_032642918.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
HV129_RS07270 1533273..1533494 - 222 WP_032642916.1 DUF987 domain-containing protein -
HV129_RS07275 1533503..1533973 - 471 WP_032642914.1 DNA repair protein RadC -
HV129_RS07280 1534006..1534827 - 822 WP_032642912.1 DUF945 domain-containing protein -
HV129_RS07285 1535048..1535488 - 441 WP_135695985.1 NirD/YgiW/YdeI family stress tolerance protein -
HV129_RS07290 1535649..1536791 - 1143 WP_029602872.1 nickel/cobalt efflux protein RcnA -
HV129_RS07295 1536804..1537073 - 270 WP_009653703.1 metal-sensing transcriptional repressor -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(12-106)

Antitoxin

Antitoxin CbeA

(4-102)


Sequences

Toxin        


Download         Length: 108 a.a.        Molecular weight: 12143.94 Da        Isoelectric Point: 6.0673

>T164105 WP_032949840.1 NZ_CP056747:c1532896-1532573 [Enterobacter hormaechei]
MQISSVPATVPVSSRLSPVMVWQQLLTYLLEHHYGLTLNDTPFHDDTAIEEHIDAGITLADAVNFLVEKYELARIDRKGF
TWREQPPFITATDILRAKKNIGLLPRS

Download         Length: 324 bp

>T164105 NZ_CP072790:c3129870-3129478 [Mycobacterium tuberculosis]
ATGACGACGGTGCTGCTCGACTCGCATGTGGCCTACTGGTGGTCGGCCGAGCCGCAGCGTCTCAGCATGGCGGCGAGCCA
GGCCATCGAACACGCCGACGAGCTCGCCGTCGCCGCGATTTCGTGGTTCGAGCTGGCTTGGCTTGCCGAACAGGAACGCA
TCCAACTGGCGATTCCGGTGCTGTCCTGGCTTCAGCAGCTGGCCGAGCACGTTCGCACCGTCGGTATCACGCCCTCGGTC
GCCGCCACGGCGGTGGCGCTGCCCTCGTCGTTCCCCGGCGATCCGGCCGACCGGTTGATCTACGCCACCGCGATCGAACA
CGGCTGGCGGCTGGTGACCAAGGACCGGCGGCTACGCAGTCATCGGCACCCACGACCGGTCACCGTCTGGTAG

Antitoxin


Download         Length: 108 a.a.        Molecular weight: 12082.82 Da        Isoelectric Point: 6.6250

>AT164105 WP_032642918.1 NZ_CP056747:c1533251-1532928 [Enterobacter hormaechei]
MQNSWGLKRDISPCFGARLVQEGCRLHFLADRAGISGTFNEEEALRLDQAFPLVMKQLELMLTTGELNPRHQHCVTLYHN
GLTCEADTLGSHGYVYIVIYPQAFATR

Download         Length: 324 bp

>AT164105 NZ_CP072790:c3130082-3129867 [Mycobacterium tuberculosis]
ATGACCGCTACGGAGGTGAAGGCGAAGATCCTCTCCTTGCTTGATGAAGTGGCCCAGGGCGAGGAGATCGAGATCACCAA
ACACGGCCGCACCGTGGCCCGGCTGGTGGCAGCGACGGGGCCGCACGCGCTGAAGGGTCGATTCTCGGGTGTGGCGATGG
CGGCCGTGGATGACGACGAACTCTTCACCACCGGGGTTTCGTGGAACGTTTCATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References