Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 506033..506534 Replicon chromosome
Accession NZ_CP056552
Organism Enterobacter sp. RHBSTW-00422

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag HV189_RS02420 Protein ID WP_050737580.1
Coordinates 506265..506534 (+) Length 90 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag HV189_RS02415 Protein ID WP_050737581.1
Coordinates 506033..506275 (+) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HV189_RS02400 502030..502770 + 741 WP_020882900.1 KDGP aldolase family protein -
HV189_RS02405 502889..504025 + 1137 WP_050737583.1 lactonase family protein -
HV189_RS02410 504045..505955 + 1911 WP_050737582.1 BglG family transcription antiterminator -
HV189_RS02415 506033..506275 + 243 WP_050737581.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
HV189_RS02420 506265..506534 + 270 WP_050737580.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
HV189_RS02425 506538..507002 - 465 WP_050737579.1 anaerobic ribonucleoside-triphosphate reductase-activating protein -
HV189_RS02430 507131..509269 - 2139 WP_020885401.1 anaerobic ribonucleoside-triphosphate reductase -
HV189_RS02435 509637..510209 - 573 WP_032681842.1 PTS sugar transporter subunit IIA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-78)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-69)


Sequences

Toxin        


Download         Length: 90 a.a.        Molecular weight: 10355.17 Da        Isoelectric Point: 10.4653

>T163656 WP_050737580.1 NZ_CP056552:506265-506534 [Enterobacter sp. RHBSTW-00422]
MTYELVFVPRAFKEWTRLGDTVKNQFKKKLANVLVTARLHGLPDCDKIKFRSQGYRLVYQVQDNVVTVCVIAIGKREKSA
VYHDVNKRL

Download         Length: 270 bp

>T163656 NZ_CP072742:4050665-4050760 [Serratia fonticola]
AACAAACCTTGCATAAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCCTTTCCCTAGACCGAGTATAGGAATCG
TACTCGGTCTTTTTTT

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 9115.58 Da        Isoelectric Point: 5.1088

>AT163656 WP_050737581.1 NZ_CP056552:506033-506275 [Enterobacter sp. RHBSTW-00422]
MATLNVRLDDKLKNEAYAVLEKLNITPTEAVRLLFQYVAETGRMPVKMVTVSDSEDELIQTVRERLANPQKGIKVRLDDL

Download         Length: 243 bp

>AT163656 NZ_CP072742:c4050762-4050674 [Serratia fonticola]
ATAAAAAAAGACCGAGTACGATTCCTATACTCGGTCTAGGGAAAGGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGC
ATTTATGCA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References