Detailed information of TA system TA163653

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/ParE-DnaT
• Location: 4492375..4492894
• Replicon: chromosome
• Accession: NZ_CP056546
• Organism: Citrobacter sp. RHBSTW-00424

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: HV191_RS21800
• Protein ID: WP_019078244.1
• Coordinates: 4492375..4492656 (-)
• Length: 94 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: HV191_RS21805
• Protein ID: WP_103283421.1
• Coordinates: 4492646..4492894 (-)
• Length: 83 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
HV191_RS21785	4489376..4489840	+	465	WP_016151476.1	anaerobic ribonucleoside-triphosphate reductase-activating protein	-
HV191_RS21790	4489862..4490383	-	522	WP_049270665.1	hypothetical protein	-
HV191_RS21795	4490383..4492347	-	1965	WP_103283422.1	type VI secretion system tip protein VgrG	-
HV191_RS21800	4492375..4492656	-	282	WP_019078244.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
HV191_RS21805	4492646..4492894	-	249	WP_103283421.1	plasmid stabilization protein	Antitoxin
HV191_RS21810	4493189..4493662	-	474	WP_016155556.1	hypothetical protein	-
HV191_RS21815	4493705..4496206	-	2502	WP_103283420.1	type VI secretion system ATPase TssH	-
HV191_RS21820	4496197..4497144	-	948	WP_103284439.1	type VI secretion system baseplate subunit TssG	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (6-82)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 94 a.a.
• Molecular weight: 10988.76 Da
• Isoelectric Point: 10.4466

>T163653 WP_019078244.1 NZ_CP056546:c4492656-4492375 [Citrobacter sp. RHBSTW-00424]
MTYNLEFLDIALKEWRKLSPALREQFKKKLAERLENPHVPAARLSGKLHRYKIKLRSAGYRLVYQVEDEQVVVLVIAVGR
RDGDEVYHQANRR

Nucleotide

• Length: 282 bp

>T163653 NZ_CP072742:3052764-3053180 [Serratia fonticola]
ATGAATAAAACCTACATGCTGGACACCAATATCTGCTCTTTTATCATGCGCGAACAGCCAGAGGCCGTGATCAGACGGTT
AGAGCAGACGGTGCTGCGTAATCACCGCATCGTGGTGTCGGCTATTACTTATGCCGAGATGCGTTTCGGGGCGATTGGCA
AAAAGGCCTCACCGCGCCATGTCCGATTGGTTGATGCCTTTTGCAGCCGCCTTGATGCGGTGCTGGCTTGGGATCGGGCT
GCGGTTGACGCGACAACAAACATTAAGGCTGCGCTTGCTGCGGCTGGCACGCCTATCGGTCCCAATGACACAGCCATCGC
TGGCCATGCCATTGCAGCTGGTGCGATTCTGGTGACCAATAACACGCGAGAGTTTGAGCGGGTAACAGGTCTGATACTGG
AAGATTGGGCAAAATAA

Antitoxin

Protein

• Length: 83 a.a.
• Molecular weight: 9073.37 Da
• Isoelectric Point: 4.5680

>AT163653 WP_103283421.1 NZ_CP056546:c4492894-4492646 [Citrobacter sp. RHBSTW-00424]
MPFHILTKTAASITDLKRNPMGTVNAGEGEAVAILNRNEPAFYCVPPAVYAYLLELVEDAELNRIADEREDGKRIKVSLN
DL

Nucleotide

• Length: 249 bp

>AT163653 NZ_CP072742:3052537-3052767 [Serratia fonticola]
ATGAGAATTGTATCGGTGTTTAAAAACGGCAATAACCGTGCTATCCGTTTGCCCCGTGATATGGACTTTGACGGCGTCAG
TGAGCTGGAAATTATCCGTGAAGGCGACAGCATCATTTTACGCCCTATTCGCCCCACTTGGGGGTCGTTCCTGCAAGAGG
AAAAAGCCGACGCGGACTTTATGATGGAACGCGAGGGGATTGTCAGCGACGAGGGACGTTTTGAACTATGA